PKC zeta (PRKCZ) (NM_002744) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC202472 |
| Predicted MW | 67.7 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002735 |
| RefSeq Size | 2359 |
| RefSeq ORF | 1776 |
| Synonyms | PKC-ZETA; PKC2 |
| Locus ID | 5590 |
| UniProt ID | Q05513 |
| Cytogenetics | 1p36.33 |
| Summary | Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2008 |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Chemokine signaling pathway, Endocytosis, Insulin signaling pathway, Tight junction, Type II diabetes mellitus |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PKC zeta" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH300438 | PRKCZ MS Standard C13 and N15-labeled recombinant protein (NP_001028753) | 10 ug |
$3,360.00
|
|
| LC400967 | Lyophilized PRKCZ HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC422406 | Lyophilized PRKCZ HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400967 | Transient overexpression lysate of protein kinase C, zeta (PRKCZ), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY422406 | Transient overexpression lysate of protein kinase C, zeta (PRKCZ), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| TP300438 | Recombinant protein of human protein kinase C, zeta (PRKCZ), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
| TP302472 | Recombinant protein of human protein kinase C, zeta (PRKCZ), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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