FADD (NM_003824) Human Mass Spec Standard

CAT#: PH301805

FADD MS Standard C13 and N15-labeled recombinant protein (NP_003815)

Request Larger Size Package

USD 1,995


Availability*
3 Weeks

Size
    • 10 ug

Product images

Specifications

Product Data
Description FADD MS Standard C13 and N15-labeled recombinant protein (NP_003815)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201805
Predicted MW 23.1 kDa
Protein Sequence
Tag C-MYC/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_003815
RefSeq Size 1873
RefSeq ORF 624
Synonyms GIG3; MORT1
Locus ID 8772
Cytogenetics 11q13.3
Summary The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents