CMBL (NM_138809) Human Mass Spec Standard

SKU
PH301711
CMBL MS Standard C13 and N15-labeled recombinant protein (NP_620164)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201711
Predicted MW 28 kDa
Protein Sequence
Protein Sequence
>RC201711 protein sequence
Red=Cloning site Green=Tags(s)

MANEAYPCPCDIGHRLEYGGLGREVQVEHIKAYVTKSPVDAGKAVIVIQDIFGWQLPNTRYIADMISGNG
YTTIVPDFFVGQEPWDPSGDWSIFPEWLKTRNAQKIDREISAILKYLKQQCHAQKIGIVGFCWGGTAVHH
LMMKYSEFRAGVSVYGIVKDSEDIYNLKNPTLFIFAENDVVIPLKDVSLLTQKLKEHCKVEYQIKTFSGQ
THGFVHRKREDCSPADKPYIDEARRNLIEWLNKYM

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_620164
RefSeq Size 4047
RefSeq ORF 735
Synonyms JS-1
Locus ID 134147
UniProt ID Q96DG6
Cytogenetics 5p15.2
Summary CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 PubMed 20177059).supplied by OMIM, Apr 2010
Protein Pathways Metabolic pathways
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Other "CMBL" proteins (3)
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LC408494 Lyophilized CMBL HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
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TP301711 Recombinant protein of human carboxymethylenebutenolidase homolog (Pseudomonas) (CMBL), 20 µg 20 ug
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