OAS1 (NM_002534) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC200696 |
| Predicted MW | 41.8 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_002525 |
| RefSeq Size | 1470 |
| RefSeq ORF | 1092 |
| Synonyms | E18/E16; IFI-4; OIAS; OIASI |
| Locus ID | 4938 |
| UniProt ID | P00973 |
| Cytogenetics | 12q24.13 |
| Summary | This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12. provided by RefSeq, Feb 2016 |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "OAS1" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC413832 | Lyophilized OAS1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC419268 | Lyophilized OAS1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY413832 | Transient overexpression lysate of 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY419268 | Transient overexpression lysate of 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP300696 | Recombinant protein of human 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
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