OAS1 (NM_002534) Human Mass Spec Standard

SKU
PH300696
OAS1 MS Standard C13 and N15-labeled recombinant protein (NP_002525)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200696
Predicted MW 41.8 kDa
Protein Sequence
Protein Sequence
>RC200696 protein sequence
Red=Cloning site Green=Tags(s)

MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGSSGKGTTL
RGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQAPRWGNPRALSFVLSSLQ
LGEGVEFDVLPAFDALGQLTGSYKPNPQIYVKLIEECTDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIR
LVKHWYQNCKKKLGKLPPQYALELLTVYAWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKN
PIIEKYLRRQLTKPRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLVRPP
ASSLPFIPAPLHEA

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_002525
RefSeq Size 1470
RefSeq ORF 1092
Synonyms E18/E16; IFI-4; OIAS; OIASI
Locus ID 4938
UniProt ID P00973
Cytogenetics 12q24.13
Summary This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12. provided by RefSeq, Feb 2016
Protein Families Druggable Genome
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Other "OAS1" proteins (5)
SKU Description Size Price
LC413832 Lyophilized OAS1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC419268 Lyophilized OAS1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY413832 Transient overexpression lysate of 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY419268 Transient overexpression lysate of 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP300696 Recombinant protein of human 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2, 20 µg 20 ug
$867.00

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