GAMT (NM_000156) Human Mass Spec Standard

SKU PH300528

GAMT MS Standard C13 and N15-labeled recombinant protein (NP_000147)

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: [RC200528]
• Predicted MW: 26.3 kDa
• Protein Sequence:
  Protein Sequence

  RC200528
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3
• Storage: Store at -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_000147
• RefSeq Size: 1138
• RefSeq ORF: 708
• Synonyms: CCDS2; HEL-S-20; PIG2; TP53I2
• Locus ID: 2593
• UniProt ID: Q14353
• Cytogenetics: 19p13.3
• Summary: The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13. [provided by RefSeq, Feb 2012]
• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, Glycine, Metabolic pathways, serine and threonine metabolism