PCMT1 (NM_005389) Human Mass Spec Standard

SKU
PH300327
PCMT1 MS Standard C13 and N15-labeled recombinant protein (NP_005380)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200327
Predicted MW 24.7 kDa
Protein Sequence
Protein Sequence
>RC200327 protein sequence
Red=Cloning site Green=Tags(s)

MAWKSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKCNPYMDSPQSIGFQATISAPHMHAYALE
LLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKDDPTLLSSGRVQLVV
GDGRMGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGNQMLEQYDKLQDGSIKMKPLMG
VIYVPLTDKEKQWSRWK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_005380
RefSeq Size 1751
RefSeq ORF 681
Synonyms PIMT
Locus ID 5110
UniProt ID P22061
Cytogenetics 6q25.1
Summary This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Oct 2011
Protein Families Druggable Genome
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Other "PCMT1" proteins (3)
SKU Description Size Price
LC417343 Lyophilized PCMT1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY417343 Transient overexpression lysate of protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1) (as WB positive control) 100 ug
$436.00
TP300327 Recombinant protein of human protein-L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1), 20 µg 20 ug
$867.00

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