PNPO (NM_018129) Human Mass Spec Standard

SKU
PH300133
PNPO MS Standard C13 and N15-labeled recombinant protein (NP_060599)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200133
Predicted MW 30 kDa
Protein Sequence
Protein Sequence
>RC200133 protein sequence
Red=Cloning site Green=Tags(s)

MTCWLRGVTATFGRPAEWPGYLSHLCGRSAAMDLGPMRKSYRGDREAFEETHLTSLDPVKQFAAWFEEAV
QCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQV
RVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQLYQDQEVPKPKSWGGYV
LYPQVMEFWQGQTNRLHDRIVFRRGLPTGDSPLGPMTHRGEEDWLYERLAP

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_060599
RefSeq Size 3482
RefSeq ORF 783
Synonyms HEL-S-302; PDXPO
Locus ID 55163
UniProt ID Q9NVS9
Cytogenetics 17q21.32
Summary The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. provided by RefSeq, Oct 2008
Protein Pathways Metabolic pathways, Vitamin B6 metabolism
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Other "PNPO" proteins (3)
SKU Description Size Price
LC413282 Lyophilized PNPO HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY413282 Transient overexpression lysate of pyridoxamine 5'-phosphate oxidase (PNPO) (as WB positive control) 100 ug
$436.00
TP300133 Recombinant protein of human pyridoxamine 5'-phosphate oxidase (PNPO), 20 µg 20 ug
$867.00

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