FAM105B (OTULIN) (NM_138348) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC224840L2V
Lenti ORF particles, OTULIN (mGFP-tagged) - Human family with sequence similarity 105, member B (FAM105B), 200ul, >10^7 TU/mL
  $1,236.00
5 Weeks*
Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol FAM105B
Synonyms AIPDS; FAM105B; GUM
Vector pLenti-C-mGFP
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC224840).
ACCN NM_138348
ORF Size 1056 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_138348.4
RefSeq Size 7896 bp
RefSeq ORF 1059 bp
Locus ID 90268
UniProt ID Q96BN8
Cytogenetics 5p15.2
MW 40.1 kDa
Summary This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. provided by RefSeq, Sep 2016
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