LARG (ARHGEF12) (NM_015313) Human Tagged ORF Clone Lentiviral Particle

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SKU
RC224785L3V
Lenti ORF particles, ARHGEF12 (Myc-DDK-tagged)-Human Rho guanine nucleotide exchange factor (GEF) 12 (ARHGEF12), transcript variant 1, 200ul, >10^7 TU/mL
  $2,531.00
5 Weeks*
Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol LARG
Synonyms LARG; PRO2792
Vector pLenti-C-Myc-DDK-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC224785).
ACCN NM_015313
ORF Size 4632 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_015313.1, NP_056128.1
RefSeq Size 9501 bp
RefSeq ORF 4635 bp
Locus ID 23365
UniProt ID Q9NZN5
Cytogenetics 11q23.3
Domains PDZ, PH, RhoGEF
Protein Pathways Axon guidance, Regulation of actin cytoskeleton, Vascular smooth muscle contraction
MW 173.1 kDa
Summary Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2014
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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