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HEPACAM (NM_152722) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC223693L4V
Lenti ORF particles, HEPACAM (mGFP-tagged) - Human hepatic and glial cell adhesion molecule (HEPACAM), 200ul, >10^7 TU/mL
file-pdf Biosafety Sheet
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
mGFP w/ Puro DDK w/ Puro
AAV Particle:
DDK
  $1,007.00
2 Weeks*
Bulk Requests & Clone Modifications

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Other products for "HEPACAM or NM_152722"

Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol HEPACAM
Synonyms GlialCAM; HEPN1; MLC2A; MLC2B
Vector pLenti-C-mGFP-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC223693).
ACCN NM_152722
ORF Size 1248 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_152722.3
RefSeq Size 3258 bp
RefSeq ORF 1251 bp
Locus ID 220296
UniProt ID Q14CZ8
Cytogenetics 11q24.2
Protein Families Druggable Genome, Transmembrane
MW 46 kDa
Summary The protein encoded by this gene is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions. The expression of this gene is downregulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene. provided by RefSeq, Jul 2011
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Documents
Resources

file-alt Citations

Inflammatory cytokines disrupt astrocyte exosomal HepaCAM-mediated protection against neuronal excitotoxicity in the SOD1G93A ALS model
Jin, Tian, Hacker et al
Sci Adv (2024) 10 (48), eadq3350 DOI: 10.1126/sciadv.adq3350
Cited by 9
AI Summary: OriGene's human HepaCAM mGFP-tagged lentiviral vector (catalog #RC223693L4V) was used to transduce astrocytes, enabling the study of HepaCAM's role in astrocyte exosome-mediated neuroprotection in the context of ALS.
Snippet: uced with 5 μl (1.3 × 1011 gc/ml) of Lenti-HepaCAM-mGFP virus. This virus was packaged by the Boston Children’s Hospital Viral Core based on a human HepaCAM mGFP-tagged HepaCAM lentiviral vector (Origene Technologies, #RC223693L4V). Three days after transduction, the medium was replaced with fresh astrocyte growth medium. The transduction efficiency was evaluated using the Keyence ALL-IN-ONE f
FigureFigureFigure
Showing 1-1 of 1 papers.
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