SMURF1 (NM_020429) Human Tagged ORF Clone Lentiviral Particle
- LentiORF®
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
|---|---|
| Tag | Myc-DDK |
| Target Symbol | SMURF1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| Mammalian Cell Selection | Puromycin |
| Sequence Data | |
| ACCN | NM_020429 |
| ORF Size | 2271 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NM_020429.1 |
| RefSeq Size | 5737 bp |
| RefSeq ORF | 2274 bp |
| Locus ID | 57154 |
| UniProt ID | Q9HCE7 |
| Cytogenetics | 7q22.1 |
| Protein Families | Druggable Genome |
| Protein Pathways | Endocytosis, TGF-beta signaling pathway, Ubiquitin mediated proteolysis |
| MW | 85.9 kDa |
| Summary | This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.provided by RefSeq, Dec 2010 |
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