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Tyrosinase (TYR) (NM_000372) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC221797L2V
Lenti ORF particles, TYR (mGFP-tagged) - Human tyrosinase (affected in oculocutaneous albinism IA) (TYR), 200ul, >10^7 TU/mL
file-pdf Biosafety Sheet
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
mGFP DDK DDK w/ Puro mGFP w/ Puro
AAV Particle:
DDK
  $1,042.00
5 Weeks*
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Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol Tyrosinase
Synonyms ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3
Vector pLenti-C-mGFP
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC221797).
ACCN NM_000372
ORF Size 1587 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_000372.3
RefSeq Size 1964 bp
RefSeq ORF 1590 bp
Locus ID 7299
UniProt ID P14679
Cytogenetics 11q14.3
Protein Families Transmembrane
Protein Pathways Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism
MW 60.39 kDa
Summary The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. provided by RefSeq, Oct 2008
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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