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ApoER2 (LRP8) (NM_004631) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC220963L3V
Lenti ORF particles, LRP8 (Myc-DDK-tagged)-Human low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (LRP8), transcript variant 1, 200ul, >10^7 TU/mL
file-pdf Biosafety Sheet
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
DDK w/ Puro DDK mGFP mGFP w/ Puro
  $1,872.00
3 Weeks*
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Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol ApoER2
Synonyms APOER2; HSZ75190; LRP-8; MCI1
Vector pLenti-C-Myc-DDK-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC220963).
ACCN NM_004631
ORF Size 2889 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_004631.3
RefSeq Size 4528 bp
RefSeq ORF 2892 bp
Locus ID 7804
UniProt ID Q14114
Cytogenetics 1p32.3
Domains EGF, EGF_CA, ldl_recept_a, ldl_recept_b
Protein Families Druggable Genome, Secreted Protein, Transmembrane
MW 105.6 kDa
Summary This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Jun 2011
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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