ULBP3 (NM_024518) Human Tagged ORF Clone Lentiviral Particle
- LentiORF®
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
|---|---|
| Tag | Myc-DDK |
| Target Symbol | ULBP3 |
| Synonyms | N2DL-3; NKG2DL3; RAET1N |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| Mammalian Cell Selection | Puromycin |
| Sequence Data | |
| ACCN | NM_024518 |
| ORF Size | 732 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NM_024518.1 |
| RefSeq Size | 735 bp |
| RefSeq ORF | 735 bp |
| Locus ID | 79465 |
| UniProt ID | Q9BZM4 |
| Cytogenetics | 6q25.1 |
| Domains | MHC_I |
| Protein Families | Druggable Genome |
| Protein Pathways | Natural killer cell mediated cytotoxicity |
| MW | 27.8 kDa |
| Summary | The protein encoded by this gene is one of several related ligands of the KLRK1/NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics. provided by RefSeq, Nov 2015 |
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