Collagen II (COL2A1) (NM_001844) Human Tagged ORF Clone Lentiviral Particle

SKU RC218041L3V

Lenti ORF particles, COL2A1 (Myc-DDK-tagged)-Human collagen, type II, alpha 1 (COL2A1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Collagen II
• Synonyms: ANFH; AOM; COL11A3; SEDC; STL1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218041).
• ACCN: NM_001844
• ORF Size: 4461 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001844.3, NP_001835.2
• RefSeq Size: 5087 bp
• RefSeq ORF: 4464 bp
• Locus ID: 1280
• UniProt ID: P02458
• Cytogenetics: 12q13.11
• Protein Pathways: ECM-receptor interaction, Focal adhesion
• MW: 141.8 kDa
• Summary: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]