ADAM12 (NM_003474) Human Tagged ORF Clone Lentiviral Particle
- LentiORF®
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
|---|---|
| Tag | Myc-DDK |
| Target Symbol | ADAM12 |
| Synonyms | ADAM12-OT1; CAR10; MCMP; MCMPMltna; MLTN; MLTNA |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| Mammalian Cell Selection | Puromycin |
| Sequence Data | |
| ACCN | NM_003474 |
| ORF Size | 2727 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NM_003474.3, NP_003465.3 |
| RefSeq Size | 5504 bp |
| RefSeq ORF | 2730 bp |
| Locus ID | 8038 |
| UniProt ID | O43184 |
| Cytogenetics | 10q26.2 |
| Domains | ACR, DISIN, Pep_M12B_propep, Reprolysin |
| Protein Families | Druggable Genome, Protease, Secreted Protein, Transmembrane |
| MW | 99.54 kDa |
| Summary | This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. provided by RefSeq, Jan 2014 |
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