DEPDC1 (NM_017779) Human Tagged ORF Clone Lentiviral Particle
- LentiORF®
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
|---|---|
| Tag | mGFP |
| Target Symbol | DEPDC1 |
| Synonyms | DEP.8; DEPDC1-V2; DEPDC1A; SDP35 |
| Vector | pLenti-C-mGFP |
| Mammalian Cell Selection | None |
| Sequence Data | |
| ACCN | NM_017779 |
| ORF Size | 1581 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NM_017779.3 |
| RefSeq Size | 4607 bp |
| RefSeq ORF | 1584 bp |
| Locus ID | 55635 |
| UniProt ID | Q5TB30 |
| Cytogenetics | 1p31.3 |
| Domains | DEP |
| MW | 61.5 kDa |
| Summary | May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.UniProtKB/Swiss-Prot Function |
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