CABLES1 (NM_138375) Human Tagged ORF Clone Lentiviral Particle

SKU RC206794L3V

Lenti ORF particles, CABLES1 (Myc-DDK tagged) - Human Cdk5 and Abl enzyme substrate 1 (CABLES1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: CABLES1
• Synonyms: CABL1; CABLES; HsT2563; IK3-1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206794).
• ACCN: NM_138375
• ORF Size: 1104 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_138375.1
• RefSeq Size: 4307 bp
• RefSeq ORF: 1107 bp
• Locus ID: 91768
• UniProt ID: Q8TDN4
• Cytogenetics: 18q11.2
• MW: 41.9 kDa
• Summary: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]