SHKBP1 (NM_138392) Human Tagged ORF Clone Lentiviral Particle

SKU RC204760L3V

Lenti ORF particles, SHKBP1 (Myc-DDK tagged) - Human SH3KBP1 binding protein 1 (SHKBP1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: SHKBP1
• Synonyms: PP203; Sb1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204760).
• ACCN: NM_138392
• ORF Size: 2121 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_138392.1
• RefSeq Size: 2379 bp
• RefSeq ORF: 2124 bp
• Locus ID: 92799
• UniProt ID: Q8TBC3
• Cytogenetics: 19q13.2
• Domains: BTB, K_tetra, WD40
• Protein Families: Ion Channels: Other
• MW: 76.3 kDa
• Summary: Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.[UniProtKB/Swiss-Prot Function]