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PHGDH (NM_006623) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC203949L2V
Lenti ORF particles, PHGDH (mGFP-tagged) - Human phosphoglycerate dehydrogenase (PHGDH), 200ul, >10^7 TU/mL
  $1,294.00
3 Weeks*
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Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol PHGDH
Synonyms 3-PGDH; 3PGDH; HEL-S-113; NLS; NLS1; PDG; PGAD; PGD; PGDH; PHGDHD; SERA
Vector pLenti-C-mGFP
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC203949).
ACCN NM_006623
ORF Size 1599 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_006623.2, NP_006614.2
RefSeq Size 2021 bp
RefSeq ORF 1602 bp
Locus ID 26227
UniProt ID O43175
Cytogenetics 1p12
Domains 2-Hacid_DH, 2-Hacid_DH_C
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Glycine, Metabolic pathways, serine and threonine metabolism
MW 56.7 kDa
Summary This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. provided by RefSeq, Aug 2011
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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