GARS (GARS1) (NM_002047) Human Tagged ORF Clone Lentiviral Particle

SKU RC202852L2V

Lenti ORF particles, GARS (mGFP-tagged) - Human glycyl-tRNA synthetase (GARS), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: GARS1
• Synonyms: CMT2D; DSMAV; GARS; GlyRS; HMN5; HMN5A; SMAD1; SMAJI
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202852).
• ACCN: NM_002047
• ORF Size: 2217 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_002047.2
• RefSeq Size: 2759 bp
• RefSeq ORF: 2220 bp
• Locus ID: 2617
• UniProt ID: P41250
• Cytogenetics: 7p14.3
• Domains: HGTP_anticodon, tRNA-synt_2b, WHEP-TRS
• Protein Pathways: Aminoacyl-tRNA biosynthesis
• MW: 83.1 kDa
• Summary: This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]