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Hemoglobin subunit epsilon (HBE1) (NM_005330) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC202247L3V
Lenti ORF particles, HBE1 (Myc-DDK tagged) - Human hemoglobin, epsilon 1 (HBE1), 200ul, >10^7 TU/mL
file-pdf Biosafety Sheet
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
DDK w/ Puro mGFP w/ Puro
AAV Particle:
DDK
  $700.00
5 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol Hemoglobin subunit epsilon
Synonyms HBE
Vector pLenti-C-Myc-DDK-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC202247).
ACCN NM_005330
ORF Size 441 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_005330.3
RefSeq Size 816 bp
RefSeq ORF 444 bp
Locus ID 3046
UniProt ID P02100
Cytogenetics 11p15.4
MW 16.2 kDa
Summary The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3' provided by RefSeq, Jul 2008
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Documents
Resources

file-alt Citations

Epsilon-Globin HBE1 Enhances Radiotherapy Resistance by Down-Regulating BCL11A in Colorectal Cancer Cells
Park, Lee, Cho et al
Cancers (Basel) (2019) 11 (4) DOI: 10.3390/cancers11040498
AI Summary: OriGene contributed to this study by providing the human HBE1 cDNA (product: RC02247), which was used to construct the HBE1 expression plasmid for transfection experiments investigating radiotherapy resistance in colorectal cancer cells.
Snippet: recovery. This process repeated for 24 treatments total 120 Gy. 4.3. Construction of the HBE1 Expression Plasmid and Transfection Human HBE1 cDNA (NM_005330) was obtained from ORIGENE (RC02247). HBE1 expression View as HTML
Showing 1-1 of 1 papers.
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