Bak (BAK1) (NM_001188) Human Tagged ORF Clone Lentiviral Particle

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SKU
RC201216L4V
Lenti ORF particles, BAK1 (mGFP-tagged) - Human BCL2-antagonist/killer 1 (BAK1), 200ul, >10^7 TU/mL
  $1,000.00
5 Weeks*
Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol Bak
Synonyms BAK; BAK-LIKE; BCL2L7; CDN1
Vector pLenti-C-mGFP-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC201216).
ACCN NM_001188
ORF Size 633 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_001188.2
RefSeq Size 2203 bp
RefSeq ORF 636 bp
Locus ID 578
UniProt ID Q16611
Cytogenetics 6p21.31
Domains Bcl-2
Protein Families Druggable Genome, Stem cell - Pluripotency, Transmembrane
MW 23.4 kDa
Summary The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. provided by RefSeq, Jul 2008
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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