DDOST (NM_005216) Human Tagged ORF Clone Lentiviral Particle
SKU
RC200672L4V
Lenti ORF particles, DDOST (mGFP-tagged) - Human dolichyl-diphosphooligosaccharide--protein glycosyltransferase (DDOST), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | DDOST |
Synonyms | AGER1; CDG1R; GATD6; OKSWcl45; OST; OST48; WBP1 |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC200672).
|
ACCN | NM_005216 |
ORF Size | 1368 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_005216.4, NP_005207.2 |
RefSeq Size | 2144 bp |
RefSeq ORF | 1320 bp |
Locus ID | 1650 |
UniProt ID | P39656 |
Cytogenetics | 1p36.12 |
Domains | DDOST_48kD |
Protein Families | Transmembrane |
Protein Pathways | Metabolic pathways, N-Glycan biosynthesis |
MW | 50.7 kDa |
Summary | This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008] |
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