Ncoa2 (NM_008678) Mouse Tagged ORF Clone Lentiviral Particle

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MR223743L4V
Lenti ORF particles, Ncoa2 (GFP-tagged) - Mouse nuclear receptor coactivator 2 (Ncoa2), transcript variant 1, 200ul, >10^7 TU/mL
  $2,426.00
5 Weeks*
Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol Ncoa2
Synonyms bHLHe75; D1Ertd433e; GRIP-1; Grip1; KAT13C; NCoA-2; SRC-2; TIF2
Vector pLenti-C-mGFP-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR223743).
ACCN NM_008678
ORF Size 4386 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_008678.2, NP_032704.2
RefSeq Size 8213 bp
RefSeq ORF 4389 bp
Locus ID 17978
UniProt ID Q61026
Cytogenetics 1 4.12 cM
Summary Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy balance between white and brown adipose tissues. Critical regulator of glucose metabolism regulation, acts as RORA coactivator to specifically modulate G6PC expression. Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3. Positively regulates the circadian clock by acting as a transcriptional coactivator for the CLOCK-ARNTL/BMAL1 heterodimer (PubMed:24529706).UniProtKB/Swiss-Prot Function
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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