Msh3 (NM_010829) Mouse Tagged ORF Clone Lentiviral Particle

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SKU
MR218117L3V
Lenti ORF particles, Msh3 (Myc-DDK-tagged) - Mouse mutS homolog 3 (E. coli) (Msh3), 200ul, >10^7 TU/mL
  $1,503.00
5 Weeks*
Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol Msh3
Synonyms D13Em1; Rep-3; Rep3
Vector pLenti-C-Myc-DDK-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR218117).
ACCN NM_010829
ORF Size 3285 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_010829.2, NP_034959.2
RefSeq Size 3945 bp
RefSeq ORF 3288 bp
Locus ID 17686
UniProt ID P13705
Cytogenetics 13 47.63 cM
Summary Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis (By similarity).UniProtKB/Swiss-Prot Function
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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