Znrf3 (NM_001080924) Mouse Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
MR215754L4V
Lenti ORF particles, Znrf3 (GFP-tagged) - Mouse zinc and ring finger 3 (Znrf3), 200ul, >10^7 TU/mL
  $1,386.00
5 Weeks*
Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol Znrf3
Synonyms Gm1167
Vector pLenti-C-mGFP-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR215754).
ACCN NM_001080924
ORF Size 2739 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_001080924.2, NP_001074393.1
RefSeq Size 6306 bp
RefSeq ORF 2742 bp
Locus ID 407821
UniProt ID Q5SSZ7
Cytogenetics 11 A1
Summary E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone (PubMed:22575959, PubMed:22895187). Along with RSPO2 and RNF43, constitutes a master switch that governs limb specification (By similarity).UniProtKB/Swiss-Prot Function
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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