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Smg8 (NM_024262) Mouse Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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MR211398L3V
Lenti ORF particles, Smg8 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1200011M11 gene (1200011M11Rik), 200ul, >10^7 TU/mL
file-pdf Biosafety Sheet
Lentiviral Particles:
DDK w/ Puro mGFP w/ Puro
  $1,458.00
5 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol Smg8
Synonyms 1200011M11Rik
Vector pLenti-C-Myc-DDK-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR211398).
ACCN NM_024262
ORF Size 2973 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_024262.1, NP_077224.1
RefSeq Size 3236 bp
RefSeq ORF 2976 bp
Locus ID 74133
UniProt ID Q8VE18
Cytogenetics 11 C
Summary Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity (By similarity).UniProtKB/Swiss-Prot Function
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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