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Bnip3l (NM_009761) Mouse Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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MR202460L4V
Lenti ORF particles, Bnip3l (GFP-tagged) - Mouse BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), 200ul, >10^7 TU/mL
file-pdf Biosafety Sheet
ORF Plasmid:
tGFP DDK
Lentiviral Particles:
mGFP w/ Puro DDK w/ Puro
  $1,000.00
3 Weeks*
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Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol Bnip3l
Synonyms C86132; D14Ertd719e; Nip3L; Nix
Vector pLenti-C-mGFP-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR202460).
ACCN NM_009761
ORF Size 654 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_009761.2, NP_033891.1
RefSeq Size 3237 bp
RefSeq ORF 657 bp
Locus ID 12177
UniProt ID Q9Z2F7
Cytogenetics 14 34.6 cM
Summary Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix (By similarity). May function as a tumor suppressor (By similarity).UniProtKB/Swiss-Prot Function
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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