TXNDC2 (NM_001098529) Human Untagged Clone

SKU
SC316404
TXNDC2 (untagged)-Human thioredoxin domain containing 2 (spermatozoa) (TXNDC2), transcript variant 2
  $567.00
3 Weeks*
Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol TXNDC2
Synonyms SPTRX; SPTRX1
Vector pCMV6 series
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for NM_001098529, the custom clone sequence may differ by one or more nucleotides
ATGGATGTAGACAAGGAACTAGGAATGGAAAGTGTTAAAGCTGGAGCCTCTGGAAAACCA
GAAATGAGGCTGGGCACTCAGGAAGAAACAAGTGAAGGTGATGCTAATGAAAGCTCATTA
CTAGTCCTGTCCAGCAACGTGCCTCTCCTGGCCCTAGAGTTCTTGGAAATAGCCCAGGCC
AAAGAGAAGGCCTTTCTCCCCATGGTCAGCCACACGTTCCACATGCGCACAGAGGAGTCT
GATGCCTCACAGGAGGGCGATGACCTACCCAAGTCCTCAGCAAACACCAGCCATCCCAAG
CAGGATGACAGCCCCAAGTCCTCAGAAGAAACCATCCAGCCCAAGGAGGGTGACATCCCC
AAGGCCCCAGAAGAAACCATCCAATCCAAGAAGGAGGACCTCCCCAAGTCCTCAGAAAAA
GCCATCCAGCCCAAAGAGAGTAACATCCCCAAGTCCTCAGCAAAACCCATCCAGCCCAAG
CTGGGCAATATTCCCAAGGCCTCAGTGAAGCCCAGCCAGCCCAAGGAGGGTGACATCCCC
AAGGCCCCAGAAGAAACCATCCAATCCAAGAAGGAGGACCTCCCCAAGTCCTCAGAAGAA
GCCATCCAGCCCAAAGAGGGTGACATCCCCAAGTCCTCAGCAAAACCCATCCAGCCCAAG
CTGGGCAATATTGCCAAGACCTCAGTGAAGCCCAGCCAGCCCAAGGAGAGTGATATCCCC
AAGTCCCCAGAAGAAACCATCCAGCCCAAGGAGGGTGACATCCCCAAGTCCTCAGCAAAG
CCCATCCAGCCCAAGCTGGGCAATATTCCCAAGGCCTCAGTGAAGCCCAGCCAGCCCAAG
GAGGGTGACATCTCCAAGTCCCCAGAAGAAGCCATCCAGCCCAAGGAGGGTGACCTCCCC
AAGTCCCTAGAGGAAGCCATCCAGCCCAAGGAGGGTGACATCCCCAAGTCCCCAGAAGAA
GCCATCCAGCCCAAGGAGGGTGACATCCCCAAGTCCCTAGAGGAAGCCATCCAGCCTAAG
GAGGGTGACATCCCCAAGTCCCCAGAAGAAACCATCCAGCCCAAGAAGGGTGACATCCCC
AAGTCCCCAGAAGAAGCCATCCAGCCCAAGGAGGGTGACATTCCCAAGTCTCCAAAACAA
GCCATCCAGCCCAAGGAGGGTGACATTCCCAAGTCCCTAGAGGAAGCCATCCCACCCAAG
GAGATTGACATCCCCAAGTCCCCAGAAGAAACCATCCAGCCCAAGGAGGATGACAGCCCC
AAGTCCCTAGAAGAAGCCACCCCATCCAAGGAGGGTGACATCCTAAAGCCTGAAGAAGAA
ACAATGGAGTTCCCGGAGGGGGACAAGGTGAAAGTGATCCTGAGCAAGGAGGACTTTGAG
GCATCACTGAAGGAGGCCGGGGAGAGGCTGGTGGCTGTGGACTTCTCGGCCACGTGGTGT
GGGCCCTGCAGGACCATCAGACCATTCTTCCATGCCCTGTCTGTGAAGCATGAGGATGTG
GTGTTCCTGGAGGTGGACGCTGACAACTGTGAGGAGGTGGTGAGAGAGTGCGCCATCATG
TGTGTCCCAACCTTTCAGTTTTATAAAAAAGAAGAAAAGGTGGATGAACTTTGCGGCGCC
CTTAAGGAAAAACTTGAAGCAGTCATTGCAGAATTAAAG
Restriction Sites Please inquire |
ACCN NM_001098529
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001098529.1, NP_001091999.1
RefSeq Size 2175 bp
RefSeq ORF 1662 bp
Locus ID 84203
UniProt ID Q86VQ3
Cytogenetics 18p11.22
Protein Families Druggable Genome
Summary Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (2) uses a different splice site, resulting in a longer open reading frame through the use of an upstream start codon, compared to variant 1. The predicted protein (isoform 2) has a longer N-terminus compared to isoform 1.
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Documents
Resources
"NM_001098529" in other vectors (2)
SKU Description Size Price
RC214547 TXNDC2 (Myc-DDK-tagged)-Human thioredoxin domain containing 2 (spermatozoa) (TXNDC2), transcript variant 2. Note: ORF is codon optimized 10 ug
$289.00 $515.00
RG214547 TXNDC2 (tGFP-tagged) - Human thioredoxin domain containing 2 (spermatozoa) (TXNDC2), transcript variant 2. Note: ORF is codon optimized 10 ug
$715.00

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