NKF3 kinase family member (PEAK1) (NM_024776) Human Untagged Clone
$1,615.00
2 Weeks*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | NKF3 kinase family member |
| Synonyms | SGK269 |
| Vector | pCMV6 series |
| Sequence Data | |
| Restriction Sites | Please inquire | |
| ACCN | NM_024776 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_024776.2, NP_079052.2 |
| RefSeq Size | 11576 bp |
| RefSeq ORF | 5241 bp |
| Locus ID | 79834 |
| UniProt ID | Q9H792 |
| Cytogenetics | 15q24.3 |
| Protein Families | Druggable Genome, Protein Kinase |
| Summary | This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. provided by RefSeq, Mar 2014 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_024776" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC212817 | PEAK1 (Myc-DDK-tagged)-Human NKF3 kinase family member (PEAK1) | 10 ug |
$1,467.00
|
|
| RC212817L1 | Lenti ORF clone of Human NKF3 kinase family member (PEAK1), Myc-DDK-tagged | 10 ug |
$1,767.00
|
|
| RC212817L3 | Lenti ORF clone of Human NKF3 kinase family member (PEAK1), Myc-DDK-tagged | 10 ug |
$1,767.00
|
|
| RG212817 | PEAK1 (tGFP-tagged) - Human NKF3 kinase family member (PEAK1) | 10 ug |
$1,867.00
|
|
Citations
Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway
Croucher, Hochgräfe, Zhang et al
Cancer Res. (2013) 73 (6), 1969-80 DOI: 10.1158/0008-5472.CAN-12-1472
Croucher, Hochgräfe, Zhang et al
Cancer Res. (2013) 73 (6), 1969-80 DOI: 10.1158/0008-5472.CAN-12-1472
Cited by 1
AI Summary: OriGene's human SgK269 cDNA in pCMV6 was used as a template to generate tagged SgK269 constructs, enabling the study of SgK269's role in basal breast cancer signaling pathways in this research.
Snippet: A cDNA encoding N-terminal HA-tagged and C-terminal His/Myc-tagged SgK269 was generated by nested PCR from a human SgK269 cDNA in pCMV6 (Origene) and cloned into the SacII and BamHI restriction sites of the pRetroX-IRES-DsRed Express vector (Clontech).
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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