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Proprotein convertase PC4 (PCSK4) (NM_017573) Human Untagged Clone

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SKU
SC311408
PCSK4 (untagged)-Human proprotein convertase subtilisin/kexin type 4 (PCSK4)
  $692.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol Proprotein convertase PC4
Synonyms PC4; SPC5
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_017573 edited
ATGCGGCCCGCCCCGATTGCGCTGTGGCTGCGCCTGGTCTTGGCCCTGGCCCTTGTCCGC
CCCCGGGCTGTGGGGTGGGCCCCGGTCCGAGCCCCCATCTATGTCAGCAGCTGGGCCGTC
CAGGTGTCCCAGGGTAACCGGGAGGTCGAGCGCCTGGCACGCAAATTCGGCTTCGTCAAC
CTGGGGCCGATCTTCCCTGACGGGCAGTACTTTCACCTGCGGCACCGGGGCGTGGTCCAG
CAGTCCCTGACCCCGCACTGGGGCCACCGCCTGCACCTGAAGAAAAACCCCAAGGTGCAG
TGGTTCCAGCAGCAGACGCTGCAGCGGCGGGTGAAACGCTCTGTCGTGGTGCCCACGGAC
CCCTGGTTCTCCAAGCAGTGGTACATGAACAGCGAGGCCCAACCAGACCTGAGCATCCTG
CAGGCCTGGAGTCAGGGGCTGTCAGGCCAGGGCATCGTGGTCTCTGTGCTGGACGATGGC
ATCGAGAAGGACCACCCGGACCTCTGGGCCAACTACGACCCCCTGGCCAGCTATGACTTC
AATGACTACGACCCGGACCCCCAGCCCCGCTACACCCCCAGCAAAGAGAACCGGCACGGG
ACCCGCTGTGCTGGGGAGGTGGCCGCGATGGCCAACAATGGCTTCTGTGGTGTGGGGGTC
GCTTTCAACGCCCGAATCGGAGGCGTACGGATGCTGGACGGTACCATCACCGATGTCATC
GAGGCCCAGTCGCTGAGCCTGCAGCCGCAGCACATCCACATTTACAGCGCCAGCTGGGGT
CCCGAGGACGACGGCCGCACGGTGGACGGCCCCGGCATCCTCACCCGCGAGGCCTTCCGG
CGTGGTGTGACCAAGGGCCGCGGCGGGCTGGGCACGCTCTTCATCTGGGCCTCGGGCAAC
GGCGGCCTGCACTACGACAACTGCAACTGCGACGGCTACACCAACAGCATCCACACGCTT
TCCGTGGGCAGCACCACCCAGCAGGGCCGCGTGCCCTGGTACAGCGAAGCCTGCGCCTCC
ACCCTCACCACCACCTACAGCAGCGGCGTGGCCACCGACCCCCAGATCGTCACCACGGAC
CTGCATCACGGGTGCACAGACCAGCACACGGGCACCTCGGCCTCAGCCCCACTGGCGGCC
GGCATGATCGCCCTAGCGCTGGAGGCCAACCCGTTCCTGACGTGGAGAGACATGCAGCAC
CTGGTGGTCCGCGCGTCCAAGCCGGCGCACCTGCAGGCCGAGGACTGGAGGACCAACGGC
GTGGGGCGCCAAGTGAGCCATCACTACGGATACGGGCTGCTGGACGCCGGGCTGCTGGTG
GACACCGCCCGCACCTGGCTGCCCACCCAGCCGCAGAGGAAGTGCGCCGTCCGGGTCCAG
AGCCGCCCCACCCCCATCCTGCCGCTGATCTACATCAGGGAAAACGTATCGGCCTGCGCC
GGCCTCCACAACTCCATCCGCTCGCTGGAGCACGTGCAGGCGCAGCTGACGCTGTCCTAC
AGCCGGCGCGGAGACCTGGAGATCTCGCTCACCAGCCCCATGGGCACGCGCTCCACACTC
GTGGCCATACGACCCTTGGACGTCAGCACTGAAGGCTACAACAACTGGGTCTTCATGTCC
ACCCACTTCTGGGATGAGAACCCACAGGGCGTGTGGACCCTGGGCCTAGAGAACAAGGGC
TACTATTTCAACACGGGGACGTTGTACCGCTACACGCTGCTGCTCTATGGGACGGCCGAG
GACATGACAGCGCGGCCTACAGGCCCCCAGGTGACCAGCAGCGCGTGTGTGCAGCGGGAC
ACAGAGGGGCTGTGCCAGGCGTGTGACGGCCCCGCCTACATCCTGGGACAGCTCTGCCTG
GCCTACTGCCCCCCGCGGTTCTTCAACCACACAAGGCTGGTGACCGCTGGGCCTGGGCAC
ACGGCGGCGCCCGCGCTGAGGGTCTGCTCCAGCTGCCATGCCTCCTGCTACACCTGCCGC
GGCGGCTCCCCGAGGGACTGCACCTCCTGTCCCCCATCCTCCACGCTGGACCAGCAGCAG
GGCTCCTGCATGGGACCCACCACCCCCGACAGCCGCCCCCGGCTTAGAGCTGCCGCCTGT
CCCCACCACCGCTGCCCAGCCTCGGCCATGGTGCTGAGCCTCCTGGCCGTGACCCTCGGA
GGCCCCGTCCTCTGCGGCATGTCCATGGACCTCCCACTATACGCCTGGCTCTCCCGTGCC
AGGGCCACCCCCACCAAACCCCAGGTCTGGCTGCCAGCTGGAACCTGA
Restriction Sites Please inquire |
ACCN NM_017573
Insert Size 2300 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_017573.3, NP_060043.2
RefSeq Size 2674 bp
RefSeq ORF 2268 bp
Locus ID 54760
UniProt ID Q6UW60
Cytogenetics 19p13.3
Protein Families Druggable Genome, Protease
Summary This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. The protease is expressed only in the testis, placenta, and ovary. It plays a critical role in fertilization, fetoplacental growth, and embryonic development and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein and pro-insulin-like growth factor II. provided by RefSeq, Jan 2014
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Documents
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"NM_017573" in other vectors (7)
SKU Description Size Price
RC218596 PCSK4 (Myc-DDK-tagged)-Human proprotein convertase subtilisin/kexin type 4 (PCSK4) 10 ug
$691.00
RC218596L1 Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 4 (PCSK4), Myc-DDK-tagged 10 ug
$991.00
RC218596L2 Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 4 (PCSK4), mGFP tagged 10 ug
$991.00
RC218596L3 Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 4 (PCSK4), Myc-DDK-tagged 10 ug
$991.00
RC218596L4 Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 4 (PCSK4), mGFP tagged 10 ug
$991.00
RG218596 PCSK4 (tGFP-tagged) - Human proprotein convertase subtilisin/kexin type 4 (PCSK4) 10 ug
$789.00 $891.00
SC318233 PCSK4 (untagged)-Human proprotein convertase subtilisin/kexin type 4 (PCSK4) 10 ug
$761.00

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