Cullin 5 (CUL5) (NM_003478) Human Untagged Clone
$715.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | Cullin 5 |
| Synonyms | CUL-5; VACM-1; VACM1 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_003478 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_003478.3, NP_003469.2 |
| RefSeq Size | 6408 bp |
| RefSeq ORF | 2343 bp |
| Locus ID | 8065 |
| UniProt ID | Q93034 |
| Cytogenetics | 11q22.3 |
| Domains | CULLIN |
| Protein Families | Druggable Genome |
| Protein Pathways | Ubiquitin mediated proteolysis |
| Summary | Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_003478" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC209273 | CUL5 (Myc-DDK-tagged)-Human cullin 5 (CUL5) | 10 ug |
$714.00
|
|
| RC209273L1 | Lenti ORF clone of Human cullin 5 (CUL5), Myc-DDK-tagged | 10 ug |
$1,014.00
|
|
| RC209273L2 | Lenti ORF clone of Human cullin 5 (CUL5), mGFP tagged | 10 ug |
$1,014.00
|
|
| RC209273L3 | Lenti ORF clone of Human cullin 5 (CUL5), Myc-DDK-tagged | 10 ug |
$1,014.00
|
|
| RC209273L4 | Lenti ORF clone of Human cullin 5 (CUL5), mGFP tagged | 10 ug |
$1,014.00
|
|
| RG209273 | CUL5 (tGFP-tagged) - Human cullin 5 (CUL5) | 10 ug |
$789.00
$914.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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