CARD14 (NM_024110) Human Untagged Clone

SKU SC305100

CARD14 (untagged)-Human caspase recruitment domain family, member 14 (CARD14), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: CARD14
• Synonyms: BIMP2; CARMA2; PRP; PSORS2; PSS1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_024110 edited; TGACTTCAGGCTCTTCCTTCTGCCCAGCTCCGTCCCACCCAGCAGCCCGCAGAGAAAGGA; GGCAGCTGGCACCACACTGGGCTTTGGAGACACTGCGGGGACTGTGGACCCCACCCTGCT; GCACGGAGCTCCTGCAAAAGCAAACCTGAGAACCTTGGGTCCTCCCAGCGCCCAGCCATG; GGGGAACTGTGCCGCAGGGACTCCGCACTCACGGCACTGGACGAGGAGACACTGTGGGAG; ATGATGGAGAGCCACCGCCACAGGATCGTACGCTGCATCTGCCCCAGCCGCCTCACCCCC; TACCTGCGCCAGGCCAAGGTGCTGTGCCAGCTGGACGAGGAGGAGGTGCTGCACAGCCCC; CGGCTCACCAACAGCGCCATGCGGGCCGGGCACTTGCTGGATTTGCTGAAGACTCGAGGG; AAGAACGGGGCCATCGCCTTCCTGGAGAGCCTGAAGTTCCACAACCCTGACGTCTACACC; CTGGTCACCGGGCTGCAGCCTGATGTTGACTTCAGTAACTTTAGCGGTCTCATGGAGACA; TCCAAGCTGACCGAGTGCCTGGCTGGGGCCATCGGCAGCCTGCAGGAGGAGCTGAACCAG; GAAAAGGGGCAGAAGGAGGTGCTGCTGCGGCGGTGCCAGCAGCTGCAGGAGCACCTGGGC; CTGGCCGAGACCCGTGCCGAGGGCCTGCACCAGCTGGAGGCTGACCACAGCCGCATGAAG; CGTGAGGTTAGCGCACACTTCCATGAGGTGCTGAGGCTGAAGGACGAGATGCTCAGCCTC; TCGCTGCACTATAGCAATGCGCTGCAGGAGAAGGAGCTGGCCGCCTCACGCTGCCGCAGC; CTGCAGGAGGAGCTGTATCTACTGAAGCAGGAGCTGCAGCGAGCCAACATGGTTTCCTCC; TGTGAGCTGGAATTGCAAGAGCAGTCCCTGAGGACAGCCAGCGACCAGGAGTCCGGGGAT; GAGGAGCTGAACCGCCTGAAGGAGGAGAATGAGAAACTGCGCTCGCTGACTTTCAGCCTG; GCGGAGAAGGACATTCTGGAGCAGAGCCTGGACGAGGCGCGGGGGAGCCGACAGGAGCTG; GTGGAGCGCATCCACTCGCTGCGGGAGCGGGCCGTGGCTGCCGAGAGGCAGCGAGAGCAG; TACTGGGAAGAGAAGGAACAGACCCTGCTGCAGTTCCAGAAGAGTAAGATGGCCTGCCAA; CTCTACAGGGAGAAGGTGAATGCGCTGCAGGCCCAGGTGTGCGAGCTGCAGAAGGAGCGA; GACCAGGCGTACTCCGCGAGGGACAGTGCTCAGAGGGAGATTTCCCAGAGCCTGGTGGAG; AAGGACTCCCTCCGCAGGCAGGTGTTCGAGCTGACGGACCAGGTCTGCGAGCTGCGCACA; CAGCTTCGCCAGCTGCAGGCAGAGCCTCCGGGTGTGCTCAAGCAGGAAGCCAGGACCAGG; GAGCCCTGTCCACGGGAGAAGCAGCGGCTGGTGCGGATGCATGCCATCTGCCCCAGAGAC; GACAGCGACTGCAGCCTCGTCAGCTCCACAGAGTCTCAGCTCTTGTCGGACCTGAGTGCC; ACGTCCAGCCGCGAGCTGGTGGACAGCTTCCGCTCCAGCAGCCCCGCGCCCCCCAGCCAG; CAGTCCCTGTACAAGCGGGTGGCCGAGGACTTCGGGGAAGAACCCTGGTCTTTCAGCAGC; TGCCTGGAGATCCCGGAGGGAGACCCGGGAGCCCTGCCGGGAGCTAAGGCAGGCGACCCA; CACCTGGATTATGAGCTCCTAGACACGGCAGACCTTCCGCAGCTGGAAAGCAGCCTGCAG; CCAGTCTCCCCTGGAAGGCTTGATGTCTCGGAGAGCGGCGTCCTCATGCGGCGGAGGCCA; GCCCGCAGGATCCTGAGCCAGGTCACCATGCTGGCGTTCCAGGGGGATGCATTGCTGGAG; CAGATCAGCGTCATCGGCGGGAACCTCACGGGCATCTTCATCCACCGGGTCACCCCGGGC; TCGGCGGCGGACCAGATGGCCTTGCGCCCGGGCACCCAGATTGTGATGGTTGATTACGAA; GCCTCAGAGCCCTTGTTCAAGGCAGTCCTGGAGGACACGACCCTGGAGGAGGCCGTGGGG; CTTCTCAGGAGGGTGGACGGCTTCTGCTGCCTGTCTGTGAAGGTCAACACGGACGGTTAT; AAGAGGCTACTCCAGGACCTGGAGGCCAAAGTGGCGACCTCGGGGGACTCATTCTACATC; CGGGTCAACCTGGCCATGGAGGGCAGGGCCAAAGGGGAGCTGCAGGTGCATTGCAACGAG; GTCCTGCACGTCACCGACACCATGTTCCAGGGCTGCGGCTGCTGGCATGCCCACCGCGTG; AACTCTTACACCATGAAGGATACTGCCGCGCACGGCACCATCCCCAACTACTCCAGGGCT; CAGCAGCAGCTCATAGCCCTCATCCAGGACATGACTCAGCAGTGCACCGTGACCCGCAAG; CCATCTTCTGGGGGACCACAGAAGCTGGTCCGCATCGTCAGTATGGACAAAGCCAAGGCC; AGCCCTCTGCGTTTGTCCTTTGACAGGGGCCAGTTGGACCCCAGCAGGATGGAGGGCTCC; AGCACGTGCTTCTGGGCCGAGAGCTGCCTCACCCTGGTGCCCTATACCCTGGTGTGGCCC; CATCGACCCGCCCGGCCCCGGCCTGTGCTCCTCGTGCCCAGGGCGGTTGGGAAGATCCTG; AGCGAGAAACTGTGCCTCCTCCAAGGGTTTAAGAAGTGCCTGGCAGAGTACTTGAGCCAG; GAGGAGTATGAGGCCTGGAGCCAGAGAGGGGACATCATCCAGGAGGGAGAGGTGTCCGGG; GGCCGCTGCTGGGTGACCCGCCATGCTGTGGAGTCCCTCATGGAAAAGAACACCCATGCC; CTCCTGGACGTCCAGCTGGACAGTGTCTGCACCCTGCACAGGATGGACATCTTCCCCATC; GTCATCCACGTCTCTGTCAACGAGAAGATGGCAAAGAAGCTCAAGAAGGGCCTACAGCGG; TTGGGCACCTCAGAGGAGCAGCTCCTGGAGGCTGCGAGGCAGGAGGAGGGAGACCTGGAC; CGGGCGCCCTGTCTATACAGCAGCCTGGCTCCTGACGGCTGGAGCGACCTGGACGGCCTG; CTCAGCTGTGTCCGCCAGGCCATCGCCGACGAGCAGAAGAAGGTGGTGTGGACGGAGCAG; AGCCCCCGATGATGCACCGTGCCCCTTCCCGGGACTGTGGGGGCTTCTGTGTGCCTGTTA; ATGCAGTCCTGTTCCTCAGCCCAGGCCCTCTTGGCACAGCTGTGGGCTCCTTGGCACATG; AGGCCGGCTCTCCCCACTGGCTGGGGTCTAACCTTGAACCCTCACCACGTGCAGGTCACA; CACAGTGAAGCCACTTGTAACTGCACACTTTTCTGTGGAAACATCTTCACCCTTTACCAG; GCTTGGCATGGTCTGAACTGGAAACCCTGAGAATGTTTCTGCAGTAGGACAGGAGGGACA; TCTTCCCATGCCTTCCCTAGAACCGGAGGCCCCGGACTTCTCTGGAAAACCGCCTGTCTG; CAGGCCCGATTCAAATCTATGGGGGCTGCACTTCCCTTTTACATTTTGATGTGTCAAAGG; CTTTTGGAGTGACCAAAAGCACAGAGGCAGCGGGTGGGGCGCCTGGGTGGTCCCCAAGGT; CGCTGCCACCCTTGCCCGGGGCAGAGGCATAAGCCCACATATGCTGTGACGCTGGCCACC; TTTTCTCAGCTTCTGAGGCTGCGATGCCTCAGGAACTCCAGTTTACAGAGACCAGTGTGT; TTACTTGTAAATAAAGCCTCTGGGTGGTGGAGACGGTACTTTCAGTGGGTCTGTGCCCCG; TGGCCCCTGTGCCTGTTCGGTGGGGGTGTCCCAGAGAAGCCTGGCACCAGTACCCCCGTA; CAAGGCCCAGCGGACTCTGCCTTCCCCTGACCTGGCTTTGCACCCCAGCCCTTCTTGGGC; CAAACATCTTTACTCCACCTTCAGGGCTCGGGGAGGACCCAGGTCCCCCAGCACCTGGCC; TTGCCCCTGCCTCCTGGGGCTGTTGCAGACTGAATGTCATTTTGACAGCAGTGTCCAAGA; ATCAGGAAGCTGTTCTAGAATTCAGGTTGGTATCATCATAAATGAGTTCAGAAAAAGAAC; TTCTGTATATTTTACTAAAATAAAAAGCTTTTACAATAAAAAAAAAAAAAAAAAA;
• Restriction Sites: Please inquire
• ACCN: NM_024110
• Insert Size: 4200 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_024110.2.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_024110.2, NP_077015.1
• RefSeq Size: 3917 bp
• RefSeq ORF: 3015 bp
• Locus ID: 79092
• UniProt ID: Q9BXL6
• Cytogenetics: 17q25.3
• Protein Families: Druggable Genome
• Summary: This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]; Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1 and 5 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.