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LRP4 (NM_002334) Human Untagged Clone

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SKU
SC303182
LRP4 (untagged)-Human low density lipoprotein receptor-related protein 4 (LRP4)
  $2,402.00
In Stock*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol LRP4
Synonyms CLSS; CMS17; LRP-4; LRP10; MEGF7; SOST2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_002334 edited
GCTCTGGCAGCACTGGAGGCGGCGGCGGCCCGAGGGCGACTTGCGGGGCGCGCAGGCCGC
CGTGCACCCGGGACGCTTCCCCCTCGGGGACCCTCCGCGGGCTTCTCCGCCGCGCCGTCC
GGCGGGAGCCGGCGGGACCCCGGGCGAGCGGCGCGGGCGGCACCATGAGGCGGCAGTGGG
GCGCGCTGCTGCTTGGCGCCCTGCTCTGCGCACACGGCCTGGCCAGCAGCCCCGAGTGTG
CTTGTGGTCGGAGCCACTTCACATGTGCAGTGAGTGCTCTTGGAGAGTGTACCTGCATCC
CTGCCCAGTGGCAGTGTGATGGAGACAATGACTGCGGGGACCACAGCGATGAGGATGGAT
GTATACTACCTACCTGTTCCCCTCTTGACTTTCACTGTGACAATGGCAAGTGCATCCGCC
GCTCCTGGGTGTGTGACGGGGACAACGACTGTGAGGATGACTCGGATGAGCAGGACTGTC
CCCCCCGGGAGTGTGAGGAGGACGAGTTTCCCTGCCAGAATGGCTACTGCATCCGGAGTC
TGTGGCACTGCGATGGTGACAATGACTGTGGCGACAACAGCGATGAGCAGTGTGACATGC
GCAAGTGCTCCGACAAGGAGTTCCGCTGTAGTGACGGAAGCTGCATTGCTGAGCATTGGT
ACTGCGACGGTGACACCGACTGCAAAGATGGCTCCGATGAGGAGAACTGTCCCTCAGCAG
TGCCAGCGCCCCCCTGCAACCTGGAGGAGTTCCAGTGTGCCTATGGACGCTGCATCCTCG
ACATCTACCACTGCGATGGCGACGATGACTGTGGAGACTGGTCAGACGAGTCTGACTGCT
CCTCCCACCAGCCCTGCCGCTCTGGGGAGTTCATGTGTGACAGTGGCCTGTGCATCAATG
CAGGCTGGCGCTGCGATGGTGACGCGGACTGTGATGACCAGTCTGATGAGCGCAACTGCA
CCACCTCCATGTGTACGGCAGAACAGTTCCGCTGTCACTCAGGCCGCTGTGTCCGCCTGT
CCTGGCGCTGTGATGGGGAGGACGACTGTGCAGACAACAGCGATGAAGAGAACTGTGAGA
ATACAGGAAGCCCCCAATGTGCCTTGGACCAGTTCCTGTGTTGGAATGGGCGCTGCATTG
GGCAGAGGAAGCTGTGCAACGGGGTCAACGACTGTGGTGACAACAGCGACGAAAGCCCAC
AGCAGAATTGCCGGCCCCGGACGGGTGAGGAGAACTGCAATGTTAACAACGGTGGCTGTG
CCCAGAAGTGCCAGATGGTGCGGGGGGCAGTGCAGTGTACCTGCCACACAGGCTACCGGC
TCACAGAGGATGGGCACACGTGCCAAGATGTGAATGAATGTGCCGAGGAGGGGTATTGCA
GCCAGGGCTGCACCAACAGCGAAGGGGCTTTCCAATGCTGGTGTGAAACAGGCTATGAAC
TACGGCCCGACCGGCGCAGCTGCAAGGCTCTGGGGCCAGAGCCTGTGCTGCTGTTCGCCA
ATCGCATCGACATCCGGCAGGTGCTGCCACACCGCTCTGAGTACACACTGCTGCTTAACA
ACCTGGAGAATGCCATTGCCCTTGATTTCCACCACCGCCGCGAGCTTGTCTTCTGGTCAG
ATGTCACCCTGGACCGGATCCTCCGTGCCAACCTCAACGGCAGCAACGTGGAGGAGGTTG
TGTCTACTGGGCTGGAGAGCCCAGGGGGCCTGGCTGTGGATTGGGTCCATGACAAACTCT
ACTGGACCGACTCAGGCACCTCGAGGATTGAGGTGGCCAATCTGGACGGGGCCCACCGGA
AGGTGTTGCTGTGGCAGAACCTGGAGAAGCCCCGGGCCATTGCCTTGCATCCCATGGAGG
GTACCATTTACTGGACAGACTGGGGCAACACCCCCCGTATTGAGGCCTCCAGCATGGATG
GCTCTGGACGCCGCATCATTGCCGATACCCATCTCTTCTGGCCCAATGGCCTCACCATCG
ACTATGCCGGGCGCCGTATGTACTGGGTGGATGCTAAGCACCATGTCATCGAGAGGGCCA
ATCTGGATGGGAGTCACCGTAAGGCTGTCATTAGCCAGGGCCTCCCGCATCCCTTCGCCA
TCACAGTGTTTGAAGACAGCCTGTACTGGACAGACTGGCACACCAAGAGCATCAATAGCG
CTAACAAATTTACGGGGAAGAACCAGGAAATCATTCGCAACAAACTCCACTTCCCTATGG
ACATCCACACCTTGCACCCCCAGCGCCAACCTGCAGGGAAAAACCGCTGTGGGGACAACA
ACGGAGGCTGCACGCACCTGTGTCTGCCCAGTGGCCAGAACTACACCTGTGCCTGCCCCA
CTGGCTTCCGCAAGATCAGCAGCCACGCCTGTGCCCAGAGTCTTGACAAGTTCCTGCTTT
TTGCCCGAAGGATGGACATCCGTCGAATCAGCTTTGACACAGAGGACCTGTCTGATGATG
TCATCCCACTGGCTGACGTGCGCAGTGCTGTGGCCCTTGACTGGGACTCCCGGGATGACC
ACGTGTACTGGACAGATGTCAGCACTGATACCATCAGCAGGGCCAAGTGGGATGGAACAG
GACAGGAGGTGGTAGTGGATACCAGTTTGGAGAGCCCAGCTGGCCTGGCCATTGATTGGG
TCACCAACAAACTGTACTGGACAGATGCAGGTACAGACCGGATTGAAGTAGCCAACACAG
ATGGCAGCATGAGAACAGTACTCATCTGGGAGAACCTTGATCGTCCTCGGGACATCGTGG
TGGAACCCATGGGCGGGTACATGTATTGGACTGACTGGGGTGCGAGCCCCAAGATTGAAC
GAGCTGGCATGGATGCCTCAGGCCGCCAAGTCATTATCTCTTCTAATCTGACCTGGCCTA
ATGGGTTAGCTATTGATTATGGGTCCCAGCGTCTATACTGGGCTGACGCCGGCATGAAGA
CAATTGAATTTGCTGGACTGGATGGCAGTAAGAGGAAGGTGCTGATTGGAAGCCAGCTCC
CCCACCCATTTGGGCTGACCCTCTATGGAGAGCGCATCTATTGGACTGACTGGCAGACCA
AGAGCATACAGAGCGCTGACCGGCTGACAGGGCTGGACCGGGAGACTCTGCAGGAGAACC
TGGAAAACCTAATGGACATCCATGTCTTCCACCGCCGCCGGCCCCCAGTGTCTACACCAT
GTGCTATGGAGAATGGCGGCTGTAGCCACCTGTGTCTTAGGTCCCCAAATCCAAGCGGAT
TCAGCTGTACCTGCCCCACAGGCATCAACCTGCTGTCTGATGGCAAGACCTGCTCACCAG
GCATGAACAGTTTCCTCATCTTCGCCAGGAGGATAGACATTCGCATGGTCTCCCTGGACA
TCCCTTATTTTGCTGATGTGGTGGTACCAATCAACATTACCATGAAGAACACCATTGCCG
TTGGAGTAGACCCCCAGGAAGGAAAGGTGTACTGGTCTGACAGCACACTGCACAGGATCA
GTCGTGCCAATCTGGATGGCTCACAGCATGAGGACATCATCACCACAGGGCTACAGACCA
CAGATGGGCTCGCGGTTGATGCCATTGGCCGGAAAGTATACTGGACAGACACGGGAACAA
ACCGGATTGAAGTGGGCAACCTGGACGGGTCCATGCGGAAAGTGTTGGTGTGGCAGAACC
TTGACAGTCCCCGGGCCATCGTACTGTACCATGAGATGGGGTTTATGTACTGGACAGACT
GGGGGGAGAATGCCAAGTTAGAGCGGTCCGGAATGGATGGCTCAGACCGCGCGGTGCTCA
TCAACAACAACCTAGGATGGCCCAATGGACTGACTGTGGACAAGGCCAGCTCCCAACTGC
TATGGGCCGATGCCCACACCGAGCGAATTGAGGCTGCTGACCTGAATGGTGCCAATCGGC
ATACATTGGTGTCACCGGTGCAGCACCCATATGGCCTCACCCTGCTCGACTCCTATATCT
ACTGGACTGACTGGCAGACTCGGAGCATCCACCGTGCTGACAAGGGTACTGGCAGCAATG
TCATCCTCGTGAGGTCCAACCTGCCAGGCCTCATGGACATGCAGGCTGTGGACCGGGCAC
AGCCACTAGGTTTTAACAAGTGCGGCTCGAGAAATGGCGGCTGCTCCCACCTCTGCTTGC
CTCGGCCTTCTGGCTTCTCCTGTGCCTGCCCCACTGGCATCCAGCTGAAGGGAGATGGGA
AGACCTGTGATCCCTCTCCTGAGACCTACCTGCTCTTCTCCAGCCGTGGCTCCATCCGGC
GTATCTCACTGGACACCAGTGACCACACCGATGTGCATGTCCCTGTTCCTGAGCTCAACA
ATGTCATCTCCCTGGACTATGACAGCGTGGATGGAAAGGTCTATTACACAGATGTGTTCC
TGGATGTTATCAGGCGAGCAGACCTGAACGGCAGCAACATGGAGACAGTGATCGGGCGAG
GGCTGAAGACCACTGACGGGCTGGCAGTGGACTGGGTGGCCAGGAACCTGTACTGGACAG
ACACAGGTCGAAATACCATTGAGGCGTCCAGGCTGGATGGTTCCTGCCGCAAAGTACTGA
TCAACAATAGCCTGGATGAGCCCCGGGCCATTGCTGTTTTCCCCAGGAAGGGGTACCTCT
TCTGGACAGACTGGGGCCACATTGCCAAGATCGAACGGGCAAACTTGGATGGTTCTGAGC
GGAAGGTCCTCATCAACACAGACCTGGGTTGGCCCAATGGCCTTACCCTGGACTATGATA
CCCGCAGGATCTACTGGGTGGATGCGCATCTGGACCGGATCGAGAGTGCTGACCTCAATG
GGAAACTGCGGCAGGTCTTGGTCGGCCATGTGTCCCACCCCTTTGCCCTCACACAGCAAG
ACAGGTGGATCTACTGGACAGACTGGCAGACCAAGTCAATCCAGCGTGTTGACAAATACT
CAGGCCGGAACAAGGAGACAGTGCTGGCAAATGTGGAAGGACTCATGGATATCATCGTGG
TTTCCCCTCAGCGGCAGACAGGGACCAATGCCTGTGGTGTGAACAATGGTGGCTGCACCC
ACCTCTGCTTTGCCAGAGCCTCGGACTTCGTATGTGCCTGTCCTGACGAACCTGATAGCC
AGCCCTGCTCCCTTGTGCCTGGCCTGGTACCACCAGCTCCTAGGGCTACTGGCATGAGTG
AAAAGAGCCCAGTGCTACCCAACACACCACCTACCACCTTGTATTCTTCAACCACCCGGA
CCCGCACGTCTCTGGAGGAGGTGGAAGGAAGATGCTCTGAAAGGGATGCCAGGCTGGGCC
TCTGTGCACGTTCCAATGACGCTGTTCCTGCTGCTCCAGGGGAAGGACTTCATATCAGCT
ACGCCATTGGTGGACTCCTCAGTATTCTGCTGATTTTGGTGGTGATTGCAGCTTTGATGC
TGTACAGACACAAAAAATCCAAGTTCACTGATCCTGGAATGGGGAACCTCACCTACAGCA
ACCCCTCCTACCGAACATCCACACAGGAAGTGAAGATTGAAGCAATCCCCAAACCAGCCA
TGTACAACCAGCTGTGCTATAAGAAAGAGGGAGGGCCTGACCATAACTACACCAAGGAGA
AGATCAAGATCGTAGAGGGAATCTGCCTCCTGTCTGGGGATGATGCTGAGTGGGATGACC
TCAAGCAACTGCGAAGCTCACGGGGGGGCCTCCTCCGGGATCATGTATGCATGAAGACAG
ACACGGTGTCCATCCAGGCCAGCTCTGGCTCCCTGGATGACACAGAGACGGAGCAGCTGT
TACAGGAAGAGCAGTCTGAGTGTAGCAGCGTCCATACTGCAGCCACTCCAGAAAGACGAG
GCTCTCTGCCAGACACGGGCTGGAAACATGAACGCAAGCTCTCCTCAGAGAGCCAGGTCT
AAATGCCCACATTCTCTTCCCTGCCTGCCTGTTCCTTCTCCTTTATGGACGTCTAGTCCT
TGTGCTCGCTTACACCGCAGGCCCCGCTTCTGTGTGCTTGTCCTCCTCCTCCTCCCACCC
CATAACTGTTCCTAAGCCTTCACCGGAGCTGTTTACCACGTGAGTCCATAACTACCTGTG
CACAAGAAATGATGGCACATCACGAGAATTTAGACCTGGATTTTACCATGAACCTCACAT
CTTGTACTCCATCCTGGGCCCCCTGAAACTGCTTATTCGTGATTCCTCACCAGCGTAGAG
CTCCACCTCCCCTTTCCCCAGTACCCTCAGTGCCTGCTTCTCAGTGCTGATGCAGCTGAT
GACCCAGGACTGCGCTCTGCCCCATCACAGCCAGCATGACTGCTTCTCTGAGAGAACTTG
CCCATCAGGGGCTGGGACATGGGGGTGTGGGTAAAGACAGGGATGAAGGATAGAGGCTGA
GAGAAGAAGGAAGAATCAGCCCAGCAGGTATGGGCATCTGGGAAACCTCCAGCCTCAAGT
GTGTTGGTAACATGAAAAAGCTCTGGGGGGTAGTTGGATCTGGGTGTCTGGTCCATTGCT
GGCAGTGGACATTATTCTTGCCCTAAGAGACACTGCCTTTTCAGCAGCAGATACTGGTGA
GATGGGGGTGGCTCAGGCTGTTCTTCCTCCTCCTAGAATGTCTGGAGCTGTTTCTACATT
CAGATAACTGGGTCCCCTATCACAAGGCTACTGGCTAATAGG
Restriction Sites Please inquire |
ACCN NM_002334
Insert Size 6600 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation The ORF of this clone has been fully sequenced and found to contain 3 SNPs compared with NM_002334.1.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_002334.1, NP_002325.1
RefSeq Size 8076 bp
RefSeq ORF 5718 bp
Locus ID 4038
UniProt ID O75096
Cytogenetics 11p11.2
Protein Families Druggable Genome, Transmembrane
Summary This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome. provided by RefSeq, May 2010
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Documents
Resources
"NM_002334" in other vectors (3)
SKU Description Size Price
RC217609 LRP4 (Myc-DDK-tagged)-Human low density lipoprotein receptor-related protein 4 (LRP4) 10 ug
$2,401.00
RC217609L1 Lenti ORF clone of Human low density lipoprotein receptor-related protein 4 (LRP4), Myc-DDK-tagged 10 ug
$2,701.00
RG217609 LRP4 (tGFP-tagged) - Human low density lipoprotein receptor-related protein 4 (LRP4) 10 ug
$2,601.00

file-alt Citations

Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors
Holdsworth, Slocombe, Doyle et al
J. Biol. Chem. (2012) 287 (32), 26464-77 DOI: 10.1074/jbc.M112.350108
Cited by 9
AI Summary: OriGene contributed full-length human cDNA clones for Wnt1, Wnt3A, Wnt9B, sclerostin, LRP4, LRP5, LRP6, and MESD, which were essential for the expression and characterization of these proteins in the study.
Snippet: Full-length human cDNA clones encoding human Wnt1, Wnt3A, Wnt9B, sclerostin, LRP4, LRP5, LRP6, and MESD were obtained from Origene. ... Fig. 4 shows that a series of the peptides (including some very short peptides) that were active in the FRET assay also inhibited the
Showing 1-1 of 1 papers.
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