PRDM1 (NM_001198) Human Untagged Clone
SKU
SC302988
PRDM1 (untagged)-Human PR domain containing 1, with ZNF domain (PRDM1), transcript variant 1
$1,085.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | PRDM1 |
| Synonyms | BLIMP1; PRDI-BF1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | Please inquire | |
| ACCN | NM_001198 |
| Insert Size | 5000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001198.2, NP_001189.1 |
| RefSeq Size | 5165 bp |
| RefSeq ORF | 2370 bp |
| Locus ID | 639 |
| UniProt ID | O75626 |
| Cytogenetics | 6q21 |
| Protein Families | Transcription Factors |
| Summary | This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. provided by RefSeq, Jul 2008 Transcript Variant: This variant (1), also known as PRDM1alpha, encodes the longer isoform (1). The protein encoded by this transcript has also been named PRDI-BF1alpha. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001198" in other vectors (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC217363 | PRDM1 (Myc-DDK-tagged)-Human PR domain containing 1, with ZNF domain (PRDM1), transcript variant 1 | 10 ug |
$1,083.00
|
|
| RC217363L1 | Lenti ORF clone of Human PR domain containing 1, with ZNF domain (PRDM1), transcript variant 1, Myc-DDK-tagged | 10 ug |
$1,383.00
|
|
| RC217363L2 | Lenti ORF clone of Human PR domain containing 1, with ZNF domain (PRDM1), transcript variant 1, mGFP tagged | 10 ug |
$1,383.00
|
|
| RC217363L3 | Lenti ORF clone of Human PR domain containing 1, with ZNF domain (PRDM1), transcript variant 1, Myc-DDK-tagged | 10 ug |
$1,383.00
|
|
| RC217363L4 | Lenti ORF clone of Human PR domain containing 1, with ZNF domain (PRDM1), transcript variant 1, mGFP tagged | 10 ug |
$1,383.00
|
|
| RG217363 | PRDM1 (tGFP-tagged) - Human PR domain containing 1, with ZNF domain (PRDM1), transcript variant 1 | 10 ug |
$1,283.00
|
|
| SC328015 | PRDM1 (untagged)-Human PR domain containing 1 with ZNF domain (PRDM1) transcript variant 1 | 10 ug |
$1,210.00
|
|
Citations
NKL homeobox gene MSX1 acts like a tumor suppressor in NK-cell leukemia
Nagel, Pommerenke, Meyer et al
Oncotarget (2017) 8 (40), 66815-66832 DOI: 10.18632/oncotarget.18609
Nagel, Pommerenke, Meyer et al
Oncotarget (2017) 8 (40), 66815-66832 DOI: 10.18632/oncotarget.18609
Snippet: Expression constructs for GATA3, HHEX, IRF4, MSX1, PCGF5 and PRDM1 were cloned in vector pCMV6 and obtained from Origene (Wiesbaden, Germany)
Showing 1-1 of 1 papers.
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