OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

PRCP (NM_199418) Human Untagged Clone

Be the first to review this product
SKU
SC128292
PRCP (untagged)-Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2
  $482.00
In Stock*
Bulk Requests & Clone Modifications

Frequently Bought Together (3)

CC100003 DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
5 x 200 ul
$170.00
PRIMER Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
100 pmol
$59.00
TF81001 TurboFectin Transfection Reagent (1 mL in 1 vial)
1 ml in 1 vial
$530.00

Other products for "PRCP or NM_199418"

Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol PRCP
Synonyms HUMPCP; PCP
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC128292 sequence for NM_199418 edited (data generated by NextGen Sequencing)
ATGGGCCGCCGAGCCCTCCTGCTCCTGCTTCTGTCTTTTCTGGCGCCCTGGGCCACCATA
GCCCTCCGGCCGGCCTTAAGGGCCCTCGGCAGCCTACACTTGCCAACCAACCCCACATCC
CTCCCGGCTGTAGCCAAGAACTATTCGGTTCTCTACTTCCAACAGAAGGCCCTTGCTGCT
GGGCAGTTGCACATATGTATTATCCAACTAAATCATTACAAGACTCCTCTGGTTGATCAT
TTTGGATTTAATACTGTGAAAACTTTTAATCAGCGGTACCTAGTAGCTGATAAATACTGG
AAGAAAAATGGTGGATCAATACTTTTCTACACTGGTAATGAAGGGGACATTATCTGGTTT
TGTAATAACACGGGGTTCATGTGGGATGTGGCTGAGGAACTGAAAGCTATGTTGGTGTTT
GCTGAACATCGATACTATGGAGAGTCTCTCCCCTTTGGTGACAACTCATTCAAGGATTCC
AGACACTTGAATTTCCTGACATCAGAACAAGCTCTGGCTGATTTTGCAGAGTTAATCAAA
CACTTGAAAAGAACAATCCCAGGAGCTGAAAATCAACCTGTCATTGCCATAGGAGGCTCC
TATGGTGGCATGCTTGCCGCCTGGTTTAGGATGAAATATCCTCATATGGTAGTTGGAGCT
CTTGCAGCTTCTGCCCCTATCTGGCAGTTTGAGGATTTAGTACCTTGTGGTGTATTTATG
AAGATCGTAACTACAGATTTTAGGAAAAGCGGTCCACATTGTTCAGAGAGCATCCACAGG
TCCTGGGATGCCATTAATCGACTCTCAAATACTGGCAGTGGTTTGCAGTGGCTTACTGGA
GCCCTTCACTTATGCAGCCCATTAACTTCTCAGGACATCCAACATTTGAAAGACTGGATC
TCTGAAACCTGGGTGAATCTGGCAATGGTGGACTATCCTTATGCCTCTAACTTTTTACAG
CCTTTGCCTGCTTGGCCTATCAAGGTAGTGTGCCAGTATTTGAAAAATCCCAATGTATCT
GATTCACTGCTGCTGCAGAATATTTTCCAAGCTCTGAATGTATATTACAATTATTCGGGC
CAGGTGAAATGCCTGAATATTTCAGAGACAGCAACTAGCAGTCTGGGAACACTGGGTTGG
AGCTATCAGGCCTGCACAGAAGTAGTCATGCCCTTTTGTACTAATGGTGTCGATGACATG
TTTGAACCTCACTCATGGAACTTAAAGGAACTTTCTGATGACTGTTTTCAACAGTGGGGT
GTGAGACCAAGGCCCTCCTGGATCACTACTATGTATGGAGGCAAAAACATTAGTTCACAC
ACAAACATTGTTTTCAGCAATGGTGAACTAGACCCCTGGTCAGGAGGTGGAGTAACTAAG
GATATCACAGACACTCTGGTTGCAGTCACCATCTCAGAGGGGGCCCACCACTTAGATCTC
CGCACCAAGAATGCCTTGGATCCTATGTCTGTGCTGTTAGCCCGCTCCTTGGAAGTTAGA
CATATGAAGAATTGGATCAGAGATTTCTATGACAGTGCGGGAAAGCAGCACTGA

Clone variation with respect to NM_199418.2
5' Read Nucleotide Sequence
>OriGene 5' read for NM_199418 unedited
GCATTGTATACGACTCCTATAGGGCGGCCGCGAATCGGCACGAGATGGGCCGCCGAGCCC
TCCTGCTCCTGCTTCTGTCTTTTCTGGCGCCCTGGGCCACCATAGCCCTCCGGCCGGCCT
TAAGGGCCCTCGGCAGCCTACACTTGCCAACCAACCCCACATCCCTCCCGGCTGTAGCCA
AGAACTATTCGGTTCTCTACTTCCAACAGAAGGCCCTTGCTGCTGGGCAGTTGCACATAT
GTATTATCCAACTAAATCATTACAAGACTCCTCTGGTTGATCATTTTGGATTTAATACTG
TGAAAACTTTTAATCAGCGGTACCTAGTAGCTGATAAATACTGGAAGAAAAATGGTGGAT
CAATACTTTTCTACACTGGTAATGAAGGGGACATTATCTGGTTTTGTAATAACACGGGGT
TCATGTGGGATGTGGCTGAGGAACTGAAAGCTATGTTGGTGTTTGCTGAACATCGATACT
ATGGAGAGTCTCTCCCCTTTGGTGACAACTCATTCAAGGATTCCAGACACTTGAATTTCC
TGACATCAGAACAAGCTCTGGCTGATTTTGCAGAGTTAATCAAACACTTGAAAAGAACAA
TCCCAGGAGCTGAAAATCAACCTGTCATTGCCATAGGAGGCTCCTATGGTGGCATGCTTG
CCGCCTGGTTTAGGATGAAATATCCTCATATGGTAGTTGGAGCTCTTGCAGCTTCTGCCC
CTATCTGGCAGTTTGAGGATTTAGTACCTTGTGGTGTATTTATGAAGATCGTAACTACAG
ATTTTAGAAAAGCGGTCCACATTGTTCAGAGAGCATCCACAAGGTCCTGGGATGCCATTA
ATCGACTCTCAATACTGGCAGTGGTTTGCAGTGGCCTTACTGGAGCCCTTCACCTTATGC
AGCCCATTAACTTCCTCAGGACCATC
Restriction Sites Please inquire |
ACCN NM_199418
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_199418.2, NP_955450.2
RefSeq Size 2224 bp
RefSeq ORF 1554 bp
Locus ID 5547
UniProt ID P42785
Cytogenetics 11q14.1
Protein Families Druggable Genome, Protease, Transmembrane
Summary This gene encodes a member of the peptidase S28 family of serine exopeptidases. The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. A pseudogene of this gene has been identified on chromosome 2. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. provided by RefSeq, Jan 2016
Transcript Variant: This variant (2) includes an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2) is longer than isoform 1. This isoform (2) may undergo proteolytic processing similar to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
"NM_199418" in other vectors (6)
SKU Description Size Price
RC212658 PRCP (Myc-DDK-tagged)-Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2 10 ug
$481.00
RC212658L1 Lenti ORF clone of Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2, Myc-DDK-tagged 10 ug
$781.00
RC212658L2 Lenti ORF clone of Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2, mGFP tagged 10 ug
$781.00
RC212658L3 Lenti ORF clone of Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2, Myc-DDK-tagged 10 ug
$781.00
RC212658L4 Lenti ORF clone of Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2, mGFP tagged 10 ug
$781.00
RG212658 PRCP (tGFP-tagged) - Human prolylcarboxypeptidase (angiotensinase C) (PRCP), transcript variant 2 10 ug
$489.00 $681.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products