PTGS1 (NM_000962) Human Untagged Clone
SKU
SC128265
PTGS1 (untagged)-Human prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (PTGS1), transcript variant 1
Product Data | |
Type | Human Untagged Clone |
---|---|
Target Symbol | PTGS1 |
Synonyms | COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
Fully Sequenced ORF
>OriGene ORF within SC128265 sequence for NM_000962 edited (data generated by NextGen Sequencing)
ATGAGCCGGAGTCTCTTGCTCCGGTTCTTGCTGTTCCTGCTCCTGCTCCCGCCGCTCCCC GTCCTGCTCGCGGACCCAGGGGCGCCCACGCCAGTGAATCCCTGTTGTTACTATCCATGC CAGCACCAGGGCATCTGTGTCCGCTTCGGCCTTGACCGCTACCAGTGTGACTGCACCCGC ACGGGCTATTCCGGCCCCAACTGCACCATCCCTGGCCTGTGGACCTGGCTCCGGAATTCA CTGCGGCCCAGCCCCTCTTTCACCCACTTCCTGCTCACTCACGGGCGCTGGTTCTGGGAG TTTGTCAATGCCACCTTCATCCGAGAGATGCTCATGCGCCTGGTACTCACAGTGCGCTCC AACCTTATCCCCAGTCCCCCCACCTACAACTCAGCACATGACTACATCAGCTGGGAGTCT TTCTCCAACGTGAGCTATTACACTCGTATTCTGCCCTCTGTGCCTAAAGATTGCCCCACA CCCATGGGAACCAAAGGGAAGAAGCAGTTGCCAGATGCCCAGCTCCTGGCCCGCCGCTTC CTGCTCAGGAGGAAGTTCATACCTGACCCCCAAGGCACCAACCTCATGTTTGCCTTCTTT GCACAACACTTCACCCACCAGTTCTTCAAAACTTCTGGCAAGATGGGTCCTGGCTTCACC AAGGCCTTGGGCCATGGGGTAGACCTCGGCCACATTTATGGAGACAATCTGGAGCGTCAG TATCAACTGCGGCTCTTTAAGGATGGGAAACTCAAGTACCAGGTGCTGGATGGAGAAATG TACCCGCCCTCGGTAGAAGAGGCGCCTGTGTTGATGCACTACCCCCGAGGCATCCCGCCC CAGAGCCAGATGGCTGTGGGCCAGGAGGTGTTTGGGCTGCTTCCTGGGCTCATGCTGTAT GCCACGCTCTGGCTACGTGAGCACAACCGTGTGTGTGACCTGCTGAAGGCTGAGCACCCC ACCTGGGGCGATGAGCAGCTTTTCCAGACGACCCGCCTCATCCTCATAGGGGAGACCATC AAGATTGTCATCGAGGAGTACGTGCAGCAGCTGAGTGGCTATTTCCTGCAGCTGAAATTT GACCCAGAGCTGCTGTTCGGTGTCCAGTTCCAATACCGCAACCGCATTGCCATGGAGTTC AACCATCTCTACCACTGGCACCCCCTCATGCCTGACTCCTTCAAGGTGGGCTCCCAGGAG TACAGCTACGAGCAGTTCTTGTTCAACACCTCCATGTTGGTGGACTATGGGGTTGAGGCC CTGGTGGATGCCTTCTCTCGCCAGATTGCTGGCCGGATCGGTGGGGGCAGGAACATGGAC CACCACATCCTGCATGTGGCTGTGGATGTCATCAGGGAGTCTCGGGAGATGCGGCTGCAG CCCTTCAATGAGTACCGCAAGAGGTTTGGCATGAAACCCTACACCTCCTTCCAGGAGCTC GTAGGAGAGAAGGAGATGGCAGCAGAGTTGGAGGAATTGTATGGAGACATTGATGCGTTG GAGTTCTACCCTGGACTGCTTCTTGAAAAGTGCCATCCAAACTCTATCTTTGGGGAGAGT ATGATAGAGATTGGGGCTCCCTTTTCCCTCAAGGGTCTCCTAGGGAATCCCATCTGTTCT CCGGAGTACTGGAAGCCGAGCACATTTGGCGGCGAGGTGGGCTTTAACATTGTCAAGACG GCCACACTGAAGAAGCTGGTCTGCCTCAACACCAAGACCTGTCCCTACGTTTCCTTCCGT GTGCCGGATGCCAGTCAGGATGATGGGCCTGCTGTGGAGCGACCATCCACAGAGCTCTGA Clone variation with respect to NM_000962.2 22 t=>c
5' Read Nucleotide Sequence
>OriGene 5' read for NM_000962 unedited
GGTTTCCGGGGTCTATCACCCGCCCGTTGCCCCAAAGGGCGGTAGGCGTGTACGGTGGGA GGTCTATATAAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTT TGCAGCGGCCGCGAATTCGGCACGAGGCACAGGAGCCTGCACTCTGCGTCCCGCACCCCA GCAGCCGCGCCATGAGCCGGAGTCTCTTGCTCCGGTTCTTGCTGTTCCTGCTCCTGCTCC CGCCGCTCCCCGTCCTGCTCGCGGACCCAGGGGCGCCCACGCCAGTGAATCCCTGTTGTT ACTATCCATGCCAGCACCAGGGCATCTGTGTCCGCTTCGGCCTTGACCGCTACCAGTGTG ACTGCACCCGCACGGGCTATTCCGGCCCCAACTGCACCATCCCTGGCCTGTGGACCTGGC TCCGGAATTCACTGCGGCCCAGCCCCTCTTTCACCCACTTCCTGCTCACTCACGGGCGCT GGTTCTGGGAGTTTGTCAATGCCACCTTCATCCGAGAGATGCTCATGCGCCTGGTACTCA CAGTGCGCTCCAACCTTATCCCCAGTCCCCCCACCTACAACTCAGCACATGACTACATCA GCTGGGAGTCTTTCTCCAACGTGAGCTATTACACTCGTATTCTGCCCTCTGTGCCTAAAG ATTGCCCCACACCCATGGGAACCAAAGGGAAAGAGCAGTTGCCAGATGCCCAGCTCCTGG CCCGCCGCTTCCTGCTNCAGAGGAAAGTCATACCTGACCCCCAGGCACCACCTCATGTTT GCCTTCTTTGCAAACACTTCACCACCAGTTCTNCAAAACTCTGGCAGATGGGNTCTGGNC TCACAAGCCCTGGGCCATGGGTAGACCTCGCCACATTTAGGAC
3' Read Nucleotide Sequence
>OriGene 3' genomic read for NM_000962 unedited
AGCACTGGNGGNAGGGGTCACAGGGNATGCCACCCGGGTTCTGTTCAGGAAAAGCTATGA CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTACAGGATAACAACTAGCATTTACACTGTATTAGGTATTA TAAGTAATCTAGAGATGATTGAAGTTTTACAGGAGATTGCACATAGGTTATATGCAAATA CTATACCACTTTATATAAAGGACTTGAGGAACCACAGATTTTGGTATCTGTAGAGATCCT GAAACAAATCCCCCACAAATACCAAAGGATGGCTGTATATAGCTTTATTTTTAAAAATTA ATTCACACAATTGTTGGGGTTGGCAAACTTCAAATCCATAGGGCAAACTAGCAGGCTGGA AACTCAGGCAGGAGTCGATGGCTATAGTCTTGAGGCAAAGTTTCTTCTTTTCCAGGAAAC TGCAGTGTTTGTTCTTGAGGCCTTTCAACTAATCAGGTGCAGCTCACCCAAATTATTTAA GTAATCTCTTTCACTTAAAGTCAACTGATTGTAGATGTTAATCACATCTACAAAATACCT TCACAGCCACACCTAGATTACTGTTTGATTAAATAACTGTGTGCTATAGCCCAACCAAAC TGACAAATAAAACCAACCATCACATCCACCAAATCAAAACTCCGGGAACAAATGTTTAAA TTACAAGCATTAAGATTCTTCCTCTGAAAAACTTTCTTGGTGCATTTAGCCTGTTTCCCT TTGCAAAACTTTCATGTGCATTTGTCATACTAAAGCAAAGTCTACCTATCTAGGCCCTTG CATTAAAG |
Restriction Sites | Please inquire |
ACCN | NM_000962 |
Insert Size | 4900 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Shipping | Ambient |
Reference Data | |
RefSeq | NM_000962.2, NP_000953.2 |
RefSeq Size | 5093 bp |
RefSeq ORF | 1800 bp |
Locus ID | 5742 |
UniProt ID | P23219 |
Cytogenetics | 9q33.2 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Arachidonic acid metabolism, Metabolic pathways |
Summary | This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] Transcript Variant: This variant (1) encodes isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Product Manuals |
FAQs |
SDS |
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RC206436L3 | Lenti ORF clone of Human prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (PTGS1), transcript variant 1, Myc-DDK-tagged | 10 ug |
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RG206436 | PTGS1 (tGFP-tagged) - Human prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (PTGS1), transcript variant 1 | 10 ug |
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MSRP
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MSRP
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.