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SOX5 (NM_006940) Human Untagged Clone

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SKU
SC127824
SOX5 (untagged)-Human SRY (sex determining region Y)-box 5 (SOX5), transcript variant 1
  $700.00
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol SOX5
Synonyms L-SOX5; L-SOX5B; L-SOX5F; LAMSHF
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC127824 sequence for NM_006940 edited (data generated by NextGen Sequencing)
ATGCTTACTGACCCTGATTTACCTCAGGAGTTTGAAAGGATGTCTTCCAAGCGACCAGCC
TCTCCGTATGGGGAAGCAGATGGAGAGGTAGCCATGGTGACAAGCAGACAGAAAGTGGAA
GAAGAGGAGAGTGACGGGCTCCCAGCCTTTCACCTTCCCTTGCATGTGAGTTTTCCCAAC
AAGCCTCACTCTGAGGAATTTCAGCCAGTTTCTCTGCTGACGCAAGAGACTTGTGGCCAT
AGGACTCCCACTTCTCAGCACAATACAATGGAAGTTGATGGCAATAAAGTTATGTCTTCA
TTTGCCCCACACAACTCATCTACCTCACCTCAGAAGGCAGAAGAAGGTGGGCGACAGAGT
GGCGAGTCCTTGTCTAGTACAGCCCTGGGAACTCCTGAACGGCGCAAGGGCAGTTTAGCT
GATGTTGTTGACACCTTGAAGCAGAGGAAAATGGAAGAGCTCATCAAAAACGAGCCGGAA
GAAACCCCCAGTATTGAAAAACTACTCTCAAAGGACTGGAAAGACAAGCTTCTTGCAATG
GGATCGGGGAACTTTGGCGAAATAAAAGGGACTCCCGAGAGCTTAGCTGAGAAAGAAAGG
CAACTCATGGGTATGATCAACCAGCTGACCAGCCTCCGAGAGCAGCTGTTGGCTGCCCAC
GATGAGCAGAAGAAACTAGCTGCCTCTCAGATTGAGAAACAGCGTCAGCAAATGGAGCTG
GCCAAGCAGCAACAAGAACAAATTGCAAGACAGCAGCAGCAGCTTCTACAGCAACAACAC
AAAATCAATTTGCTCCAGCAACAGATCCAGGTTCAAGGTCAGCTGCCGCCATTAATGATT
CCCGTATTCCCTCCTGATCAACGGACACTGGCTGCAGCTGCCCAGCAAGGATTCCTCCTC
CCTCCAGGCTTCAGCTATAAGGCTGGATGTAGTGACCCTTACCCTGTTCAGCTGATCCCA
ACTACCATGGCAGCTGCTGCCGCAGCAACACCAGGCTTAGGCCCACTCCAACTGCAGCAG
TTATATGCTGCCCAGCTAGCTGCAATGCAGGTATCTCCAGGAGGGAAGCTGCCAGGCATA
CCCCAAGGCAACCTTGGTGCTGCTGTATCTCCTACCAGCATTCACACAGACAAGAGCACA
AACAGCCCACCACCCAAAAGCAAGGATGAAGTGGCACAGCCACTGAACCTATCAGCTAAA
CCCAAGACCTCTGATGGCAAATCACCCACATCACCCACCTCTCCCCATATGCCAGCTCTG
AGAATAAACAGTGGGGCAGGCCCCCTCAAAGCCTCTGTCCCAGCAGCGTTAGCTAGTCCT
TCAGCCAGAGTTAGCACAATAGGTTACTTAAATGACCATGATGCTGTCACCAAGGCAATC
CAAGAAGCTCGGCAAATGAAGGAGCAACTCCGACGGGAACAACAGGTGCTTGATGGGAAG
GTGGCTGTTGTGAATAGTCTGGGTCTCAATAACTGCCGAACAGAAAAGGAAAAAACAACA
CTGGAGAGTCTGACTCAGCAACTGGCAGTTAAACAGAATGAAGAAGGAAAATTTAGCCAT
GCAATGATGGATTTCAATCTGAGTGGAGATTCTGATGGAAGTGCTGGAGTCTCAGAGTCA
AGAATTTATAGGGAATCCCGAGGGCGTGGTAGCAATGAACCCCACATAAAGCGTCCAATG
AATGCCTTCATGGTGTGGGCTAAAGATGAACGGAGAAAGATCCTTCAAGCCTTTCCTGAC
ATGCACAACTCCAACATCAGCAAGATATTGGGATCTCGCTGGAAAGCTATGACAAACCTA
GAGAAACAGCCATATTATGAGGAGCAAGCCCGTCTCAGCAAGCAGCACCTGGAGAAGTAC
CCTGACTATAAGTACAAGCCCAGGCCAAAGCGCACCTGCCTGGTGGATGGCAAAAAGCTG
CGCATTGGTGAATACAAGGCAATCATGCGCAACAGGCGGCAGGAAATGCGGCAGTACTTC
AATGTTGGGCAACAAGCACAGATCCCCATTGCCACTGCTGGTGTTGTGTACCCTGGAGCC
ATCGCCATGGCTGGGATGCCCTCCCCTCACCTGCCCTCGGAGCACTCAAGCGTGTCTAGC
AGCCCAGAGCCTGGGATGCCTGTTATCCAGAGCACTTACGGTGTGAAAGGAGAGGAGCCA
CATATCAAAGAAGAGATACAGGCCGAGGACATCAATGGAGAAATTTATGATGAGTACGAC
GAGGAAGAGGATGATCCAGATGTAGATTATGGGAGTGACAGTGAAAACCATATTGCAGGA
CAAGCCAACTGA

Clone variation with respect to NM_006940.4
5' Read Nucleotide Sequence
>OriGene 5' read for NM_006940 unedited
GCGGATTCGGCACGAGGAGAGAGAGAAAATAATTGGTTTAGAAGGTTTGGACTCACTTGA
CAGGTTCAGTTGGAGACGATCATAGGTGGCTGCTGTGACAAAGGGAAATTGTGCTTTTCC
AGCATGCTTACTGACCCTGATTTACCTCAGGAGTTTGAAAGGATGTCTTCCAAGCGACCA
GCCTCTCCGTATGGGGAAGCAGATGGAGAGGTAGCCATGGTGACAAGCAGACAGAAAGTG
GAAGAAGAGGAGAGTGACGGGCTCCCAGCCTTTCACCTTCCCTTGCATGTGAGTTTTCCC
AACAAGCCTCACTCTGAGGAATTTCAGCCAGTTTCTCTGCTGACGCAAGAGACTTGTGGC
CATAGGACTCCCACTTCTCAGCACAATACAATGGAAGTTGATGGCAATAAAGTTATGTCT
TCATTTGCCCCACACAACTCATCTACCTCACCTCAGAAGGCAGAAGAAGGTGGGCGACAG
AGTGGCGAGTCCTTGTCTAGTACAGCCCTGGGAACTCCTGAACGGCGCAAGGGCAGTTTA
GCTGATGTTGTTGACACCTTGAAGCAGAGGAAAATGGAAGAGCTCATCAAAAACGAGCCG
GAAGAAACCCCCAGTATTGAAAAACTACTCTCANAGGACTGGAAAGACAAGCTTCTTGCN
ATGGGATCGGNGAACTTTGGCGAAATAAAAGGGACTCCCGAGAGCTTAGCTGAGAAAGAA
GGGCACTCATGGGTATGATCAACCAGCTGACCCACCTTCGAAAGCAGCTGTTGGCTGCCC
ACGATGAGCAGAANGAACTAGCTGCCTCTCAGATGAGAAACAGCGTCAGCAAATGGAACT
GCCCAAGCAGCAACAAGAACAAATTGGCAGACAGCG
3' Read Nucleotide Sequence
>OriGene 3' read for NM_006940 unedited
GGGGGGGAATTTTGGTGGNTAACNCCAATTCNCGTGTTNNNTNGAATCCATTTACCAAAA
TTATAAATCTCTCAAGCCAAAAAGCAATGTAGTAACACAGTAAGTTGCTATTCATAGCAC
CTTTTATCAAGTGACTTCAAAGCACTTTCAACATTAATATAACTATTTTTGCTTTTGTTT
TCTTTTGGGGAAAACTAGGGCAAAGAAAACCGATGNCTAAGTAANAACCGTCAGAACAAG
AGAACAGAATGCAGCGGTATGAACTTGCTTTTTGATTCGGTTCATGCACAGTTTAGTGTT
GGACATAAACCTAACTAAAATCAAATTTTGAATTTCAGCAGTTAAAAGTCACCATTAACA
ATTTTGTTTTCCCCTTCAAATAAAACAAAATATAACAAAAAAAAGACCAAACACCAAAGT
GTTGTCAATTCATCGGGAAGTGTGTTAGAATTGATTTCAGCCATGAATGCCTTGAATGGC
ATCTACCTGGAGCTAAAACAAAGTATTCTTGTAGCCCAAACCCATGAAACGAAAACAAAG
CATCCGTAATAACCCGGGGTGCCACTAAAGTGTCCGCAAAAGGGGGAGGGGAACCCCCTC
AAACCGGAGGGAGGCGGGGGTAAGCGCGAGCACCCCATTCCCCGGCAATCGCGTGGCACC
GCACACAAAAAGGGATTACAAAAGGACTGGCCGGAGCGAGCCCGCTCCCGGGGGGCCTAG
CCACCGAAAGTAGGAACCCGCAACCACATGCGGCCCGACAGGTCCCCCCCAAAGCCCGGG
ANTAACCAGACCGGAGGGGCGTCACACCGTCCGCCCAGCATGGTAACCGAAAGGTACCAT
CAATGTGACCCCGCGAGCGCGCCCGCCCCCCCTCCG
Restriction Sites NotI-NotI |
ACCN NM_006940
Insert Size 4700 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_006940.4, NP_008871.3
RefSeq Size 4333 bp
RefSeq ORF 2292 bp
Locus ID 6660
UniProt ID P35711
Cytogenetics 12p12.1
Domains HMG
Protein Families Transcription Factors
Summary This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene. provided by RefSeq, Jul 2008
Transcript Variant: This variant (1) encodes the longest isoform (a, also called L-SOX5A). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
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Documents
Resources
"NM_006940" in other vectors (6)
SKU Description Size Price
RC224228 SOX5 (Myc-DDK-tagged)-Human SRY (sex determining region Y)-box 5 (SOX5), transcript variant 1 10 ug
$699.00
RC224228L1 Lenti ORF clone of Human SRY (sex determining region Y)-box 5 (SOX5), transcript variant 1, Myc-DDK-tagged 10 ug
$999.00
RC224228L2 Lenti ORF clone of Human SRY (sex determining region Y)-box 5 (SOX5), transcript variant 1, mGFP tagged 10 ug
$999.00
RC224228L3 Lenti ORF clone of Human SRY (sex determining region Y)-box 5 (SOX5), transcript variant 1, Myc-DDK-tagged 10 ug
$999.00
RC224228L4 Lenti ORF clone of Human SRY (sex determining region Y)-box 5 (SOX5), transcript variant 1, mGFP tagged 10 ug
$999.00
RG224228 SOX5 (tGFP-tagged) - Human SRY (sex determining region Y)-box 5 (SOX5), transcript variant 1 10 ug
$789.00 $899.00

file-alt Citations

Osteochondral Tissue Regeneration Through Polymeric Delivery of DNA Encoding for the SOX Trio and RUNX2
Needham, Shah, Dahlin et al
Acta Biomater (2014)
Cited by 58
AI Summary: OriGene contributed plasmid DNA encoding for RUNX2, SOX5, SOX6, and SOX9, which were used to promote bone and cartilage tissue regeneration in the study's gene delivery experiments.
Snippet: [6] and [9]. Plasmid DNA encoding for RUNX2, SOX5, SOX6, and SOX9 (Origene, Rockville, MD) was expanded using DNA expansion kits according to the manufacturer's instructions (Qiagen, Venlo, Netherlands), collected, and used directly. ... Cite SaveSaving
Development of a Polymeric Gene Delivery Vector for Application in Osteochondral Tissue Engineering
Needham
Thesis (2014)
Snippet: Plasmid DNA encoding for RUNX2, SOX5, SOX6, and SOX9 (Origene, Rockville, MD) was expanded using DNA expansion kits according to the manufacturer's instructions (Qiagen, Venlo, Netherlands), collected, and used directly
Showing 1-2 of 2 papers.
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