NOMO2 (NM_173614) Human Untagged Clone

SKU SC127595

NOMO2 (untagged)-Human NODAL modulator 2 (NOMO2), transcript variant 2

Product Data

• Type: Human Untagged Clone
• Target Symbol: NOMO2
• Synonyms: Nomo; PM5
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_173614, the custom clone sequence may differ by one or more nucleotides; ; ; ATGCTGGTGGGCCAGGGCGCGGGGCTGCTGGGGCCCGCGGTGGTCACCGCCGCGGTGGTGCTGCTGCTGA; GCGGCGTGGGGCCGGCGCACGGCTCGGAGGACATCGTGGTGGGCTGCGGTGGCTTCGTCAAGTCGGACGT; GGAGATCAACTACTCGCTCATCGAGATAAAGCTGTACACCAAGCATGGGACTTTGAAATACCAGACAGAC; TGTGCCCCTAATAATGGTTACTTTATGATCCCTTTGTATGATAAGGGGGATTTCATTCTGAAGATTGAGC; CTCCCCTAGGGTGGAGTTTTGAGCCGACGACCGTGGAGCTCCATGTGGATGGAGTCAGTGACATCTGCAC; AAAGGGTGGGGACATCAACTTTGTCTTCACTGGGTTCTCTGTGAATGGCAAGGTCCTCAGCAAAGGGCAG; CCCCTGGGTCCTGCGGGAGTTCAGGTGTCTCTGAGAAACACTGGGACCGAAGCAAAGATCCAGTCCACAG; TTACACAGCCTGGCGGAAAGTTTGCATTTTTTAAAGTTCTGCCTGGAGATTATGAAATCCTCGCAACTCA; TCCAACCTGGGCGTTGAAAGAGGCAAGCACCACAGTGCGTGTAACCAACTCCAATGCCAATGCGGCCAGT; CCCCTCATAGTTGCTGGCTACAATGTGTCTGGCTCTGTCCGAAGTGATGGGGAGCCCATGAAAGGGGTGA; AGTTTCTTCTCTTTTCTTCTTTAGTAACTAAAGAGGATGTCCTGGGCTGCAATGTCTCACCAGTGCCTGG; GTTCCAGCCCCAAGACGAGAGTCTGGTGTATTTGTGCTACACGGTCTCCAGAGAAGATGGCTCGTTCTCT; TTCTATTCCTTGCCAAGTGGGGGCTACACTGTGATTCCGTTCTATCGAGGGGAGAGGATTACCTTTGATG; TGGCGCCTTCCAGACTTGACTTCACAGTGGAGCATGACAGCTTGAAAATCGAGCCCGTGTTCCACGTCAT; GGGATTCTCCGTCACCGGGAGGGTCTTGAACGGACCCGAAGGAGATGGTGTTCCAGAAGCAGTAGTCACC; CTGAATAACCAAATCAAAGTTAAAACAAAAGCTGATGGCTCATTCCGCCTTGAGAACATAACCACAGGGA; CATACACCATCCATGCTCAGAAAGAGCACCTCTACTTTGAAACGGTCACCATCAAAATTGCACCGAACAC; ACCTCAGCTGGCTGACATTGTTGCAACAGGGTTCAGTGTCTGTGGTCGGATATCAATCATTCGCTTCCCG; GACACCGTCAAGCAGATGAATAAATACAAAGTTGTCCTGTCATCTCAAGACAAGGACAAGTCTTTGGTCA; CCGTGGAGACAGATGCTCATGGATCATTTTGTTTTAAAGCAAAACCAGGGACTTACAAAGTGCAGGTGAT; GGTTCCTGAGGCAGAAACCAGAGCAGGGCTGACGTTGAAACCCCAGACATTTCCTCTTACTGTGACCGAC; AGGCCCGTGATGGATGTGGCCTTTGTACAGTTCTTGGCATCAGTTTCTGGGAAAGTCTCTTGTTTGGACA; CCTGTGGTGACTTGCTGGTGACTCTACAGTCCCTGAGCCGCCAGGGTGAGAAGCGGAGCCTCCAGCTCTC; CGGCAAGGTCAACGCCATGACTTTCACCTTTGACAACGTGCTCCCTGGAAAATACAAAATAAGCATCATG; CATGAGGATTGGTGCTGGAAGAACAAGAGCCTGGAGGTGGAAGTGCTGGAGGATGACGTGTCTGCAGTTG; AGTTCAGGCAGACGGGCTACATGCTGAGATGTTCCCTGTCTCACGCCATCACTCTGGAATTTTATCAGGA; TGGAAATGGGCGTGAGAATGTGGGGATTTATAACCTCTCCAAAGGAGTCAACCGATTCTGCCTGTCCAAG; CCTGGTGTGTACAAAGTGACCCCTCGCTCCTGCCACCGGTTTGAGCAAGCGTTCTACACCTATGACACGT; CTTCACCTAGTATCTTGACATTGACAGCCATTCGCCACCATGTCCTTGGAACTATCACCACCGACAAAAT; GATGGATGTCACTGTGACTATCAAGTCTTCCATCGACAGTGAACCCGCCTTGGTCTTAGGCCCTCTGAAG; TCTGTGCAGGAGCTGCGGAGGGAGCAGCAGCTGGCTGAGATCGAGGCCCGCAGGCAGGAGAGGGAGAAAA; ACGGCAATGAGGAAGGTGAAGAAAGAATGACCAAGCCTCCCGTGCAGGAGATGGTAGATGAGTTACAAGG; CCCCTTCTCGTATGATTTCTCTTACTGGGCGCGGTCTGGAGAGAAAATCACTGTTACACCGTCATCTAAA; GAGCTGCTCTTTTATCCCCCTTCAATGGAAGCCGTTGTCAGTGGAGAAAGCTGCCCAGGGAAGCTGATCG; AGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTTGGAAGGAGTCGAGATTGT; CATCAGTGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAGTGTT; GGCCCCCTGCACAGTGACCTGGAGTACACGGTGACCTCACAGAAGGAGGGCTATGTTCTGACTGCAGTGG; AAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAGGCGTAAGCTTTGAGATAAAAGCTGAGGATGA; CCAGCCCCTCCCGGGAGTCCTCTTATCCCTGAGTGGTGGCCTGTTTCGTTCCAACCTCTTGACCCAGGAC; AACGGCATTCTGACATTCTCAAACCTGAGCCCTGGCCAGTATTACTTCAAACCCATGATGAAGGAGTTCC; GGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCCAGAACCTGAAGATCACCATCACGGGGTA; CCGAACCGCTTACAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGGTTGCCATG; GAAGCGGTGGGCCAGAACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCA; GATTACGTGGATTGCTGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAACGACCACATTGA; GCGGGCGCTCCCCCACCATAGGGTGATTGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTT; TTCCGGCAGATTAATCAATTTGATTTAAGTGGAAATGTGATCACTTCCTCTGAATACCTTCCTACGTTAT; GGGTCAAGCTTTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTT; CTTCCATTTCCCCCCACTGCTCAGAGATGGCGAGAACTATGTTGTGCTTCTGGACTCCACACTCCCCAGA; TCCCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTTGA; TTTTTAATCCCACGAGGAAGCTGCCTGAACAGGACATCGCACAAGGATCCTACATTGCCCTGCCATTGAC; GCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGCTCATTCCTTTGCTGCTGCAGTTGACAAGCCGG; CTACAGGGAGTCGGCGCGCTCGGCCAGGCAGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAG; CCAAGAAACAGAAGACAAGGCGGACGTGA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_173614 unedited; GGATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCGGCGTGCA; GTGTGAGGGGCGGGACCCGGCTGCCGGCGGTGGGTCTAGCTGGGGGAGGTCGGGCCATGC; TGGTGGGCCAGGGCGCGGGGCCGCTGGGGCCCGCGGTGGTCACCGCCGCGGTGGTGCTGC; TGCTGAGCGGCGTGGGGCCGGCGCACGGCTCGGAGGACATCGTGGTGGGCTGCGGTGGCT; TCGTCAAGTCGGACGTGGAGATCAACTACTCTCTCATCGAGATAAAGCTGTACACCAAGC; ATGGGACTTTGAAATACCAGACAGACTGTGCCCCTAATAATGGTTACTTTATGATCCCTT; TGTATGATAAGGGGGATTTCATTCTGAAGATTGAGCCTCCCCTAGGGTGGAGTTTTGAGC; CGACGACCGTGGAGCTCCATGTGGATGGAGTCAGTGACATCTGCACAAAGGGTGGGGACA; TCAACTTTGTCTTCACTGGGTTCTCTGTGAATGGCAAGGTCCTCAGCAAAGGGCAGCCCC; TGGGTCCTGCGGGAGTTCAGGTGTCTCTGAGAAACACTGGGACCGAAGCAAAGATCCAGT; CCACAGTTACACAGCCTGGCGGAAAGTTTGCATTTTTTAAAGTTCTGCCTGGAGATTATG; AAATCCTCGCAACTCATCCAACCTTGGGCGTTGAAAGAGGCAAGCACCACAGTGGCGTGT; AACCAACTCCAATGCCAATGCGGCCAGTCCCCTCATAANTTGCTGGGCTACATGTTGTCT; GGCTCTGNTCCGAAAGTGATGGGGAGCCCATGAAGGGGGGNGAAAGTTCTTCTCTTTTCT; TCTTTAGTACTAAAAAAGGATGTCCTGGGCTGCATGTCTCACAGTGCN;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_173614 unedited; GCACGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGACAAAATAATAATAAATTATA; TTTGACTCAGAAAATAAATTCTGTTCAGCAGAGTGACAGGAGGGTCCATTCATTGCATTG; CACGAGGGGCTCTACGGAGGGGTGAGGATGGGTGCAGGATGCCACAGTGACAAGGGACAT; GGGGTGCGGGCCCAGCAGCACAGGCTGAAGTTAGCTGACGCATGCTTTTGGCTTTTATCC; CACGGGCGGGTAGTGGCCGGACCCCTGGCTGTGGCCTGTCCCAAGTGAGACTGCAACTGT; CCCCTTCCTCCTCACGTCCGCCTTGTCTTCTGTTTCTTGGCTTGTCTCTTTGCATCTTCT; GGGCCGCTATTGTCAGAAGCTGCCTGGCCGAGCGCGCCGACTCCCTGTAGCCGGCTTGTC; AACTGCAGCAGCAAAGGAATGAGCTTGTCATGGTTGTAACCGGCCAGCAGAACCAGCAGC; GTCAATGGCAGGGCAATGTAGGATCCTTGTGCGATGTCCTGTTCAGGCAGCTTCCTCGTG; GGATTAAAAATCAAGGTGATGTGTTTATGGTAGCCCACTGCGGTGAAAGAAACTTGAGGC; AAGATGTAGTCATACTGGGATCTGGGGAGTGTGGAGTCCAGAAGCACACATAGTTCTCGC; CATCTCTGAGCAGTGGGGGGAAATGAANAACAGGGACTGCCCAGGGAAACTGTCTGGATT; GATTGTCCAGTTTTCGCTTTGTAAGCTTGACCATACCGTAGAGGTTTCAAAGAATGATAC; CTTTCCCTTAATCAATTGATTACCGCCGAAACTTGATGTTACTCATNGAGCATTATCCAA; CTCATACCCTTGTGGGGGACCCGCTAAGGGNCGTTGCTTTGCCTGACCGACGGGACCAAT; CCGGGAAAATCCGAATTGACTGCCTTTTTTGTACGGTTTTCC;
• Restriction Sites: NotI-NotI
• ACCN: NM_173614
• Insert Size: 4000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_173614.2, NP_775885.1
• RefSeq Size: 4317 bp
• RefSeq ORF: 3669 bp
• Locus ID: 283820
• UniProt ID: Q5JPE7
• Cytogenetics: 16p12.3
• Summary: This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (2) contains an alternate segment in the 3' CDS, compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus compared to isoform 1.