ULBP2 (NM_025217) Human Untagged Clone

SKU SC122983

ULBP2 (untagged)-Human UL16 binding protein 2 (ULBP2)

Product Data

• Type: Human Untagged Clone
• Target Symbol: ULBP2
• Synonyms: ALCAN-alpha; N2DL2; NKG2DL2; RAET1H; RAET1L
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_025217 edited; GTCTCTCCTCCCTAGCGCTCTGGGTCCTTAATGGCAGCAGCCGCCGCTACCAAGATCCTT; CTGTGCCTCCCGCTTCTGCTCCTGCTGTCCGGCTGGTCCCGGGCTGGGCGAGCCGACCCT; CACTCTCTTTGCTATGACATCACCGTCATCCCTAAGTTCAGACCTGGACCACGGTGGTGT; GCGGTTCAAGGCCAGGTGGATGAAAAGACTTTTCTTCACTATGACTGTGGCAACAAGACA; GTCACACCTGTCAGTCCCCTGGGGAAGAAACTAAATGTCACAACGGCCTGGAAAGCACAG; AACCCAGTACTGAGAGAGGTGGTGGACATACTTACAGAGCAACTGCGTGACATTCAGCTG; GAGAATTACACACCCAAGGAACCCCTCACCCTGCAGGCCAGGATGTCTTGTGAGCAGAAA; GCTGAAGGACACAGCAGTGGATCTTGGCAGTTCAGTTTCGATGGGCAGATCTTCCTCCTC; TTTGACTCAGAGAAGAGAATGTGGACAACGGTTCATCCTGGAGCCAGAAAGATGAAAGAA; AAGTGGGAGAATGACAAGGTTGTGGCCATGTCCTTCCATTACTTCTCAATGGGAGACTGT; ATAGGATGGCTTGAGGACTTCTTGATGGGCATGGACAGCACCCTGGAGCCAAGTGCAGGA; GCACCACTCGCCATGTCCTCAGGCACAACCCAACTCAGGGCCACAGCCACCACCCTCATC; CTTTGCTGCCTCCTCATCATCCTCCCCTGCTTCATCCTCCCTGGCATCTGAGGAGAGTCC; TTTAGAGTGACAGGTTAAAGCTGATACCAAAAGGCTCCTGTGAGCACGGTCTTGATCAAA; CTCGCCCTTCTGTCTGGCCAGCTGCCCACGACCTACGGTGTATGTCCAGTGGCCTCCAGC; AGATCATGATGACATCATGGACCCAATAGCTCATTCACTGCCTTGATTCCTTTTGCCAAC; AATTTTACCAGCAGTTATACCTAACATATTATGCAATTTTCTCTTGGTGCTACCTGATGG; AATTCCTGCACTTAAAGTTCTGGCTGACTAAACAAGATATATCATTTTCTTTCTTCTCTT; TTTGTTTGGAAAATCAAGTACTTCTTTGAATGATGATCTCTTTCTTGCAAATGATATTGT; CAGTAAAATAATCACGTTAGACTTCAGACCTCTGGGGATTCTTTCCGTGTCCTGAAAGAG; AATTTTTAAATTATTTAATAAGAAAAAATTTATATTAATGATTGTTTCCTTTAGTAATTT; ATTGTTCTGTACTGATATTTAAATAAAGAGTTCTATTTCCCAAAAAAAAAAAAAAAAAAA; AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_025217 unedited; GTCATTTTTGTATACGACTCACTATAGGCGGCCGCGACTTCATATCTGGTACCGGTCCGG; AATTCCCGGGATGTCTCTCCTCCCTAGCGCTCTGGGTCCTTAATGGCAGCAGCCGCCGCT; ACCAAGATCCTTCTGTGCCTCCCGCTTCTGCTCCTGCTGTCCGGCTGGTCCCGGGCTGGG; CGAGCCGACCCTCACTCTCTTTGCTATGACATCACCGTCATCCCTAAGTTCAGACCTGGA; CCACGGTGGTGTGCGGTTCAAGGCCAGGTGGATGAAAAGACTTTTCTTCACTATGACTGT; GGCAACAAGACAGTCACACCTGTCAGTCCCCTGGGGAAGAAACTAAATGTCACAACGGCC; TGGAAAGCACAGAACCCAGTACTGAGAGAGGTGGTGGACATACTTACAGAGCAACTGCGT; GACATTCAGCTGGAGAATTACACACCCAAGGAACCCCTCACCCTGCAGGCCAGGATGTCT; TGTGAGCAGAAAGCTGAAGGACACAGCAGTGGATCTTGGCAGTTCAGTTTCGATGGGCAG; ATCTTCCTCCTCTTTGACTCAGAGAAGAGAATGTGGACAACGGTTCATCCTGGAGCCAGA; TAGATGAAAGATAAGTGGGAGAATGACAAGGTTGTGGCCATGTCCTTCCATTACTTCTCA; ATGGGAGACTGTATAGGATGGCTTGAGGACTTCTTGATGGGCATGGACAGCACCCTGGAG; CCAAGTGCANGAGCACCACTCGCCATGTCCTCATGCACAACCCAACTCAGGGCCACAGCC; ACCACCCTCATCCTTTGCTGCCTCCCATCATCCTCCCCTGCTTCATCCTCCCTGGCATCT; GAGGAGAGTCCTTTAAATGACAGGTAAAAGCTGATCCAAAAGGCTCCTGTGAACACGGTC; CTGAATCAACTCGCCCTTTGTCTGGCCACCG;
• Restriction Sites: Please inquire
• ACCN: NM_025217
• Insert Size: 1368 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_025217.2, NP_079493.1
• RefSeq Size: 1362 bp
• RefSeq ORF: 741 bp
• Locus ID: 80328
• UniProt ID: Q9BZM5
• Cytogenetics: 6q25.1
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Natural killer cell mediated cytotoxicity
• Summary: This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015]