OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Lin28 (LIN28A) (NM_024674) Human Untagged Clone

Be the first to review this product
SKU
SC122965
LIN28A (untagged)-Human lin-28 homolog A (LIN28A)
  $300.00
In Stock*
Bulk Requests & Clone Modifications

Frequently Bought Together (4)

TA324388 LIN28A Antibody (Center)
400 ul
$645.00
CC100003 DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
5 x 200 ul
$170.00
PRIMER Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
100 pmol
$59.00
TF81001 TurboFectin Transfection Reagent (1 mL in 1 vial)
1 ml in 1 vial
$530.00

Other products for "Lin28 or NM_024674"

Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol Lin28
Synonyms CSDD1; LIN-28; lin-28A; LIN28; ZCCHC1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_024674 edited
GTGCGGGGGAAGATGTAGCAGCTTCTTCTCCGAACCAACCCTTTGCCTTCGGACTTCTCC
GGGGCCAGCAGCCGCCCGACCAGGGGCCCGGGGCCACGGGCTCAGCCGACGACCATGGGC
TCCGTGTCCAACCAGCAGTTTGCAGGTGGCTGCGCCAAGGCGGCAGAAGAGGCGCCCGAG
GAGGCGCCGGAGGACGCGGCCCGGGCGGCGGACGAGCCTCAGCTGCTGCACGGTGCGGGC
ATCTGTAAGTGGTTCAACGTGCGCATGGGGTTCGGCTTCCTGTCCATGACCGCCCGCGCC
GGGGTCGCGCTCGACCCCCCAGTGGATGTCTTTGTGCACCAGAGTAAGCTGCACATGGAA
GGGTTCCGGAGCTTGAAGGAGGGTGAGGCAGTGGAGTTCACCTTTAAGAAGTCAGCCAAG
GGTCTGGAATCCATCCGTGTCACCGGACCTGGTGGAGTATTCTGTATTGGGAGTGAGAGG
CGGCCAAAAGGAAAGAGCATGCAGAAGCGCAGATCAAAAGGAGACAGGTGCTACAACTGT
GGAGGTCTAGATCATCATGCCAAGGAATGCAAGCTGCCACCCCAGCCCAAGAAGTGCCAC
TTCTGCCAGAGCATCAGCCATATGGTAGCCTCATGTCCGCTGAAGGCCCAGCAGGGCCCT
AGTGCACAGGGAAAGCCAACCTACTTTCGAGAGGAAGAAGAAGAAATCCACAGCCCTACC
CTGCTCCCGGAGGCACAGAATTGAGCCACAATGGGTGGGGGCTATTCTTTTGCTATCAGG
AAGTTTCGAGGAGCAGGCAGAGTGGAGAAAGTGGGAATAGGGTGCATTGGGGCTAGTTGG
CACTGCCATGTATCTCAGGCTTGGGTTCACACCATCACCCTTTCTTCCCTCTAGGTGGGG
GGAAAGGGTGAGTCAAAGGAACTCCAACCATGCTCTGTCCAAATGCAAGTGAGGGTTCTG
GGGGCAACCAGGAGGGGGGAATCACCCTACAACCTGCATACTTTGAGTCTCCATCCCCAG
AATTTCCAGCTTTTGAAAGTGGCCTGGATAGGGAAGTTGTTTTCCTTTTAAAGAAGGATA
TATAATAATTCCCATGCCAGAGTGAAATGATTAAGTATAAGACCAGATTCATGGAGCCAA
GCCACTACATTCTGTGGAAGGAGATCTCTCAGGAGTAAGCATTGTTTTTTTTTCACATCT
TGTATCCTCATACCCACTTTTGGGATAGGGTGCTGGCAGCTGTCCCAAGCAATGGGTAAT
GATGATGGCAAAAAGGGTGTTTGGGGGAACAGCTGCAGACCTGCTGCTCTATGCTCACCC
CCGCCCCATTCTGGGCCAATGTGATTTTATTTATTTGCTCCCTTGGATACTGCACCTTGG
GTCCCACTTTCTCCAGGATGCCAACTGCACTAGCTGTGTGCGAATGACGTATCTTGTGCA
TTTTAACTTTTTTTCCTTAATATAAATATTCTGGTTTTGTATTTTTGTATATTTTAATCT
AAGGCCCTCATTTCCTGCACTGTGTTCTCAGGTACATGAGCAATCTCAGGGATAGCCAGC
AGCAGCTCCAGGTCTGCGCAGCAGGAATTACTTTTTGTTGTTTTTGCCACCGTGGAGAGC
AACTATTTGGAGTGCACAGCCTATTGAACTACCTCATTTTTGCCAATAAGAGCTGGCTTT
TCTGCCATAGTGTCCTCTTGAAACCCCCTCTGCCTTGAAAATGTTTTATGGGAGACCAGG
TTTTAACTGGGTGGCCCCATGACTTGATTGCCTTCTACTGGAAGATTGGGAATTAGTCTA
AACAGGAAATGGTGGTACACAGAGGCTAGGAGAGGCTGGGCCCGGTGAAAAGGCCAGAGA
GCAAGCCAAGATTAGGTGAGGGTTGTCTAATCCTATGGCACAGGACGTGCTTTACATCTC
CAGATCTGTTCTTCACCAGATTAGGTTAGGCCTACCATGTGCCACAGGGTGTGTGTGTGT
TTGTAAAACTAGAGTTGCTAAGGATAAGTTTAAAGACCAATACCCCTGTACTTAATCCTG
TGCTGTCGAGGGATGGATATATGAAGTAAGGTGAGATCCTTAACCTTTCAAAATTTTCGG
GTTCCAGGGAGACACACAAGCGAGGGTTTTGTGGTGCCTGGAGCCTGTGTCCTGCCCTGC
TACAGTAGTGATTAATAGTGTCATGGTAGCTAAAGGAGAAAAAGGGGGTTTCGTTTACAC
GCTGTGAGATCACCGCAAACCTACCTTACTGTGTTGAAACGGGACAAATGCAATAGAACG
CATTGGGTGGTGTGTGTCTGATCCTGGGTTCTTGTCTCCCCTAAATGCTGCCCCCCAAGT
TACTGTATTTGTCTGGGCTTTGTAGGACTTCACTACGTTGATTGCTAGGTGGCCTAGTTT
GTGTAAATATAATGTATTGGTCTTTCTCCGTGTTCTTTGGGGGTTTTGTTTACAAACTTC
TTTTTGTATTGAGAGAAAAATAGCCAAAGCATCTTTGACAGAAGGTTCTGCACCAGGCAA
AAAGATCTGAAACATTAGTTTGGGGGGCCCTCTTCTTAAAGTGGGGATCTTGAACCATCC
TTTCTTTTGTATTCCCCTTCCCCTATTACCTATTAGACCAGATCTTCTGTCCTAAAAACT
TGTCTTCTACCCTGCCCTCTTTTCTGTTCACCCCCAAAAGAAAACTTACACACCCACACA
CATACACATTTCATGCTTGGAGTGTCTCCACAACTCTTAAATGATGTATGCAAAAATACT
GAAGCTAGGAAAACCCTCCATCCCTTGTTCCCAACCTCCTAAGTCAAGACCATTACCATT
TCTTTCTTTCTTTTTTTTTTTTTTTAAAATGGAGTCTCGCTGTGTCGCCCAGGCTGGAGT
GCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGGTTACAGAGCAAGACTCTGTCTC
AAACAAAACAAAACAAAACAAAAACACACTACTGTATTTTGGATGGATCAAACCTCCTTA
ATTTTAATTTCTAATCCTAAAGTAAAGAGATGCAATTGGGGGCCTTCCATGTAGAAAGTG
GGGTCAGGAGGCCAAGAAAGGGAATATGAATGTATATCCAAGTCACTCAGGAACTTTTAT
GCAGGTGCTAGAAACTTTATGTCAAAGTGGCCACAAGATTGTTTAATAGGAGACGAACGA
ATGTAACTCCATGTTTACTGCTAGAAACCAAAGCTTTGTGTAAAATCTTGAATTTATGGG
GCGGGAGGGTAGGAAAGCCTGTACCTGTCTGTTTTTTTCCTGATCCTTTTCCCTCATTCC
TGAACTGCAGGAGACTGAGCCCCTTTGGGCTTTGGTGACCCCATCACTGGGGTGTGTTTA
TTTGATGGTTGATTTTGCTGTACTGGGTACTTCCTTTCCCATTTTCTAATCATTTTTTAA
CACAAGCTGACTCTTCCCTTCCCTTCTCCTTTCCCTGGAAAAATACAATGAATAAATAAA
GACTTATTGGTACTCAAAAAAAAAAAAAAAAAA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_024674 unedited
NNNNCCCAGTACACAATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACGAGGG
TGCGGGGGAAGAGTAGCAGCTTCTTCTCCGAACCAACCCTTTGCCTTCGGACTTCTCCGG
GGCCAGCAGCCGCCCGANAGGGGCCCGGGGCCACGGGCTCAGCCGACGACCATGGGCTCC
GTGTCCAACCAGCAGTTTGCAGGTGGCTGCGCCAAGGCGGCAGAAGAGGCGCCCGAGGAG
GCGCCGGAGGACGCGGCCCGGGCGGCGGACGAGCCTCAGCTGCTGCACGGTGCGGGCATC
TGTAAGTGGTTCAACGTGCGCATGGGGTTCGGCTTCCTGTCCATGACCGCCCGCGCCGGG
GTCGCGCTCGACCCCCCAGTGGATGTCTTTGTGCACCAGAGTAAGCTGCACATGGAAGGG
TTCCGGAGCTTGAAGGAGGGTGAGGCAGTGGAGTTCACCTTTAAGAAGTCAGCCAAGGGT
CTGGAATCCATCCGTGTCACCGGACCTGGTGGAGTATTCTGTATTGGGAGTGAGAGGCGG
CCAAAAGGAAAGAGCATGCAGAAGCGCAGATCAAAAGGAGACAGGTGCTACAACTGTGGA
GGTCTAGATCATCATGCCAAGGAATGCAAGCTGCCACCCCAGCCCAAGAAGTGCCACTTC
TGCCAGAGCATCAGCCATATGGTAGCCTCATGTCCGCTGAAAGCCCAGCAGGGCCCTAGT
GCACAGGGAAAGCCAACCTACTTTCGAGAGGAAGAAANAAGAAATCCACAGCCCTACCCT
GCTCCCGGAGGCACAGAATTGAGCCACATGGGTGGGGGCTATTCTTTTGCTATCAGGAAG
TTTCGAGGACAGGCAGAGN
Restriction Sites Please inquire |
ACCN NM_024674
Insert Size 630 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_024674.3, NP_078950.1
RefSeq Size 3513 bp
RefSeq ORF 630 bp
Locus ID 79727
UniProt ID Q9H9Z2
Cytogenetics 1p36.11
Protein Families Transcription Factors
Summary This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. provided by RefSeq, Sep 2015
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
"NM_024674" in other vectors (6)
SKU Description Size Price
RC203397 LIN28A (Myc-DDK-tagged)-Human lin-28 homolog A (LIN28A) 10 ug
$300.00
RC203397L1 Lenti ORF clone of Human lin-28 homolog A (LIN28A), Myc-DDK-tagged 10 ug
$600.00
RC203397L2 Lenti ORF clone of Human lin-28 homolog A (LIN28A), mGFP tagged 10 ug
$600.00
RC203397L3 Lenti ORF clone of Human lin-28 homolog A (LIN28A), Myc-DDK-tagged 10 ug
$600.00
RC203397L4 Lenti ORF clone of Human lin-28 homolog A (LIN28A), mGFP tagged 10 ug
$600.00
RG203397 LIN28A (tGFP-tagged) - Human lin-28 homolog A (LIN28A) 10 ug
$489.00 $500.00

file-alt Citations

Lin 28A/Occludin axis: An aberrantly activated pathway in intestinal epithelial cells leading to impaired barrier function under total parenteral nutrition
Liu, Gong, Zhou et al
FASEB J (2020)
AI Summary: OriGene's Lin 28A expression vector (SC122965) was used to overexpress Lin 28A in experimental models, enabling the authors to investigate its role in repressing Occludin translation and impairing intestinal barrier function under total parenteral nutrition.
Snippet: Abstract Disassembly of tight junctions is a major cause of intestinal barrier dysfunction under total parenteral nutrition (TPN), but the precise mechanisms have not been fully understood. Normall...;Lin 28A expression vector (SC122965) was purchased from Origene (Rockville, MD). …
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products