beta Sarcoglycan (SGCB) (NM_000232) Human Untagged Clone
SKU
SC120022
SGCB (untagged)-Human sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB)
$300.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | beta Sarcoglycan |
| Synonyms | A3b; LGMD2E; LGMDR4; SGC |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_000232 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_000232.3, NP_000223.1 |
| RefSeq Size | 4229 bp |
| RefSeq ORF | 957 bp |
| Locus ID | 6443 |
| UniProt ID | Q16585 |
| Cytogenetics | 4q12 |
| Domains | sarcoglycan |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Viral myocarditis |
| Summary | This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.provided by RefSeq, Oct 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_000232" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC204699 | SGCB (Myc-DDK-tagged)-Human sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB) | 10 ug |
$300.00
|
|
| RC204699L3 | Lenti ORF clone of Human sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB), Myc-DDK-tagged | 10 ug |
$600.00
|
|
| RC204699L4 | Lenti ORF clone of Human sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB), mGFP tagged | 10 ug |
$600.00
|
|
| RG204699 | SGCB (tGFP-tagged) - Human sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB) | 10 ug |
$489.00
$500.00
|
|
Citations
Evidence of associations of APOBEC3B gene deletion with susceptibility to persistent HBV infection and hepatocellular carcinoma
Zhang, Cai, Chang et al
Hum. Mol. Genet. (2013) 22 (6), 1262-9 DOI: 10.1093/hmg/dds513
Zhang, Cai, Chang et al
Hum. Mol. Genet. (2013) 22 (6), 1262-9 DOI: 10.1093/hmg/dds513
Cited by 59
AI Summary: OriGene’s A3B expression plasmid was used as the template to amplify full-length A3B cDNA for functional studies in this paper investigating the role of APOBEC3B gene deletion in HBV infection and liver cancer.
Snippet: Total RNA was isolated from the liver samples using Trizol reagent (Life Technologies, Carlsbad, CA, USA). ... A full-length of A3B cDNA was amplified from A3B expression plasmid (OriGene, Rockville, MD, USA) with the primers 5′-atctaagcttgccaccatgaatccacagatcagaaatccg-3
SGCE missense mutations that cause myoclonus-dystonia syndrome impair {varepsilon}-sarcoglycan trafficking to the plasma membrane: modulation by ubiquitination and torsinA,
Esapa, Waite, Locke et al
Hum Mol Genet (2007)
Esapa, Waite, Locke et al
Hum Mol Genet (2007)
AI Summary: In the paper "SGCE missense mutations that cause myoclonus-dystonia syndrome impair ε-sarcoglycan trafficking to the plasma membrane: modulation by ubiquitination and torsinA," OriGene products such as the SGCE Myc-DDK-tagged cDNA clone and anti-DDK (FLAG) antibody were used for expressing and detecting mutant and wild-type ε-sarcoglycan proteins, enabling the study of their cellular localization and trafficking defects.
Showing 1-2 of 2 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
