FOLR2 (NM_000803) Human Untagged Clone

SKU SC119666

FOLR2 (untagged)-Human folate receptor 2 (fetal) (FOLR2), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: FOLR2
• Synonyms: BETA-HFR; FBP; FBP/PL-1; FOLR1; FR-BETA; FR-P3; FRbeta
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119666 sequence for NM_000803 edited (data generated by NextGen Sequencing); ATGGTCTGGAAATGGATGCCACTTCTGCTGCTTCTGGTCTGTGTAGCCACCATGTGCAGT; GCCCAGGACAGGACTGATCTCCTCAATGTCTGTATGGATGCCAAGCACCACAAGACAAAG; CCAGGTCCTGAGGACAAGCTGCATGACCAATGCAGTCCCTGGAAGAAGAATGCCTGCTGC; ACAGCCAGCACCAGCCAGGAGCTGCACAAGGACACCTCCCGCCTGTACAACTTTAACTGG; GACCACTGCGGCAAGATGGAGCCCGCCTGCAAGCGCCACTTCATCCAGGACACCTGTCTC; TATGAGTGCTCACCCAACCTGGGGCCCTGGATCCAGCAGGTGAATCAGAGCTGGCGCAAA; GAACGCTTCCTGGATGTGCCCTTATGCAAAGAGGACTGTCAGCGCTGGTGGGAGGATTGT; CACACCTCCCACACGTGCAAGAGCAACTGGCACAGAGGATGGGACTGGACCTCAGGAGTT; AACAAGTGCCCAGCTGGGGCTCTCTGCCGCACCTTTGAGTCCTACTTCCCCACTCCAGCT; GCCCTTTGTGAAGGCCTCTGGAGTCACTCATACAAGGTCAGCAACTACAGCCGAGGGAGC; GGCCGCTGCATCCAGATGTGGTTTGATTCAGCCCAGGGCAACCCCAACGAGGAAGTGGCG; AGGTTCTATGCTGCAGCCATGCATGTGAATGCTGGTGAGATGCTTCATGGGACTGGGGGT; CTCCTGCTCAGTCTGGCCCTGATGCTGCAACTCTGGCTCCTTGGCTGA; ; Clone variation with respect to NM_000803.4;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000803 unedited; TTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGTCTACCCTGTACCGAA; GACAGAGGCTGTGGGGACAGCCTAGGGGCCTGGATCTATTGCCTACTTAGAGAGAGGCCA; ACTCAGACACAGCCGTGTATGCTCCCAGCAGCAACGGAGGTTCAGCTCCGCCTGCAGGGA; CAGAAAGACATGGTCTGGAAATGGATGCCACTTCTGCTGCTTCTGGTCTGTGTAGCCACC; ATGTGCAGTGCCCAGGACAGGACTGATCTCCTCAATGTCTGTATGGATGCCAAGCACCAC; AAGACAAAGCCAGGTCCTGAGGACAAGCTGCATGACCAATGCAGTCCCTGGAAGAAGAAT; GCCTGCTGCACAGCCAGCACCAGCCAGGAGCTGCACAAGGACACCTCCCGCCTGTACAAC; TTTAACTGGGACCACTGCGGCAAGATGGAGCCCGCCTGCAAGCGCCACTTCATCCAGGAC; ACCTGTCTCTATGAGTGCTCACCCAACCTGNGGCCCTGGATCCAGCAGGTGAATCAGAGC; TGGCGCAAAGAACGCTTCCTGGATGTGCCCTTATGCAAAGAGGACTGTCAGCGCTGGTGG; GAGGATTGTCACACCTCCCACACGTGCAAGAGCAACTGGCACAGAGGATGGGACTGGACC; TCANGAGTTAACAAGTGCCCAGCTGGGGCTCTCTGCCGCACCTTTGAGTCCTACTTCCCC; ACTNCAGCTGCCCTTTGTGAAGGCCTNCTGGAGTCACTCATACANGGGTCAGCACTACAG; CCGAGGGAGCGGCCGCTGCATCCAGATTGTGGTTTGATTCAGCCAGGGCAACCCACGAGG; AAGGGGCGAGTTCTTGCTGCAGCATGCATGGATGCTGNGAGAGCTCATGGACCTGGGGTC; TCTGCTCATCTGGCCTGAG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000803 unedited; ATGAACCGCGGCACGCAATCTATAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT; TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCTTTTTATAAAAAAACAATCTGTTTATTA; AAAAGGACTTTTGGCCCCCCCATGGAACAACAACAAACTGGGGGACAAAGGGTTAGGGGA; CTAAAAAAACCATGCTTAAGGGGCTGTCTTTTGGGGGAACTGAACTGACCCCACCCTGGT; TATCCAAACTGAGGGCAGGTATTCTGGGAGGACTGAACTCACCCAAGGAGCCAAATTTGC; ACCATCAGGGCCAAACTGAACAGGAAACCCCCAGTCCCATGAAACATTTCACCAACATTC; ACATGCATGGGTGGAGAAAAAAACCCCCCCACTTCCTCGTTGGGGTTGCCCTGGGCTGAA; TCAAACCACATTTGGATGCAGGGGCCGCTCCCTCGGGTGTAATTGCTGACCTTGTATAAA; GGACCCCAAAGGCCTTCCCAAAGGGCATCTGGAGGGGGGAATTAGGACTCAAAGGGGCGG; CAAAAAGCCCCAGCTGGGCCCTTGTTAACTCCTGAGGCCCAATCCCATCCTTTGTGCCAA; TTGCTCTTGCACGTGGGGGAAGTGTGACAATCCTCCCACCAACGCTAGAAGTTCCTTTTG; CATAAGGGCACATCCAGGAAAGCGTTCTTTGCGCCACTTCTGATTCACCTGCTGGATACA; CAGCCCCAGGGTGGGGTGAGCCCTCTTAAAAAAAGGGTCCTGGAATAAATGGCCCTTGGA; AGCCGGCTCCTTTTGCCCGAGGGGCCCAAGTTAAGTTGTCAGGCGGGAGGGGGCCCTTGG; CACCCTCTGGTGGGGGCGGGGTGGCCAAAAGCATTTTTTTCCAGGGACTGGTTTGGCATG; CAACTTGTTCTCAGACCCGTCTTTTTTTTGGGGGGCTGCGCCCCATAAAACCTGGGGGAA; AAAACCCCGCCTCGGCCTGGCAAGGGGGCTCAAAAAACAAAAA;
• Restriction Sites: NotI-NotI
• ACCN: NM_000803
• Insert Size: 1240 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000803.2, NP_000794.1
• RefSeq Size: 1119 bp
• RefSeq ORF: 768 bp
• Locus ID: 2350
• UniProt ID: P14207
• Cytogenetics: 11q13.4
• Domains: Folate_rec
• Protein Families: Druggable Genome, Secreted Protein
• Summary: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (1) represents the longest transcript. All variants (1-4) encode the same protein.