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CREBL2 (NM_001310) Human Untagged Clone

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SKU
SC119296
CREBL2 (untagged)-Human cAMP responsive element binding protein-like 2 (CREBL2)
  $150.00
In Stock*
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Specifications
Specifications
Product Data
Type Human Untagged Clone
Target Symbol CREBL2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC119296 sequence for NM_001310 edited (data generated by NextGen Sequencing)
ATGGATGACAGTAAGGTGGTTGGAGGCAAAGTAAAGAAGCCCGGTAAACGTGGTCGGAAG
CCAGCCAAAATTGACTTGAAAGCAAAACTTGAGAGGAGCCGGCAGAGTGCAAGAGAATGC
CGAGCCCGAAAAAAGCTGAGATATCAGTATTTGGAAGAGTTGGTATCCAGTCGAGAAAGA
GCTATATGTGCCCTCAGAGAGGAACTGGAAATGTACAAGCAGTGGTGCATGGCAATGGAC
CAAGGAAAAATCCCTTCTGAAATAAAGGCCCTACTCACTGGAGAAGAGCAGAACAAATCT
CAGCAGAACTCAAGCAGGCATACCAAGGCTGGGAAGACAGATGCTAATAGCAATTCCTGG
TGA

Clone variation with respect to NM_001310.2
5' Read Nucleotide Sequence
>OriGene 5' read for NM_001310 unedited
GTAACACGACTTACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGCTCTGCCATTCCTG
AACTGGTCCCTCGTCCCCGTGACTCTGGCATCAGGGAAGCGAACTGTTAGGCGAGAGGAG
GAGGCAGCCAGAACCATATCCCCTTCTTCCTCGGGGCGGGGGCCGGGCCAGGCCGGCTGA
GCCGGGGGAGGGCTCCGGGAGGGAGTGCCTGGCCAGGCCGGCCTGTCTGCCGCGATGGAT
GACAGTAAGGTGGTTGGAGGCAAAGTAAAGAAGCCCGGTAAACGTGGTCGGAAGCCAGCC
AAAATTGACTTGAAAGCAAAACTTGAGAGGAGCCGGCAGAGTGCAAGAGAATGCCGAGCC
CGAAAAAAGCTGAGATATCAGTATTTGGAAGAGTTGGTATCCAGTCGAGAAAGAGCTATA
TGTGCCCTCAGAGAGGAACTGGAAATGTACAAGCAGTGGTGCATGGCAATGGACCAAGGA
AAAATCCCTTCTGAAATAAAGGCCCTACTCACTGGAGAAGAGCAGAACAAATCTCAGCAG
AACTCAAGCAGGCATACCAAGGCTGGGAAGACAGATGCTAATAGCAATTCCTGGTGAAGA
TTATATAAAGATGAGTCAGTGATTGAAGCCAATATTCTGATTCCCATGGAAGATGGATGG
GCAAGAGTGTACTTCTTGGCTCCATTTACTACCTACTGCTCAGTAGTCATCTCTGTAAAT
CTGCAATTTCTACCANAATGTGTGATCGTAGATCTCAAAGGGATCTGCTNTAAACTNTCA
CACTTAGAAATNCTACCAACATTCAGACCTGTCTGGGNTTGTATTGNCACCCATGACNAT
TNAACATGTTGTGATGCTTNGAAACACANGAGTAGAGAAAATCGATGAAGATTGATTTTT
TGCACCTNAACTCCACATNGCTTTATGGNNTN
3' Read Nucleotide Sequence
>OriGene 3' read for NM_001310 unedited
AATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTAATCAGTGACATTTATTAACATGCTTC
AAAAGTGACCAAAGTGTCCAGCCAGCACAATAGCCGAGGCAATCAACGTTCTCTTAGTGT
GTGATCTCCTCCAAAACACCAAATAAATAGGTTTAGGAATAACCTCAAATAAATTGTAAT
TTAACTTCGCCCAAAATTATACATCCTCTACTGCTCTTCCCTGCTCCTGTAAAGATACTA
GCGGGAGGGGAGAAAGCTCAAATGACTCTGTAATTTAGAATTACAACCAGAGAAGAAATA
CTTCAAGCACAATAAAGACGTTCCATTGAAGAGCGACATTCATTCTGGAATGTTTGTTTT
GAAAACAACTCTTCTGGGGGAATTCAAAAGGTACTGAACAAAGCAACATAAAGTAAGTTT
TGGGTTATTTTGCAAAATAAAAATATACAATTGAGTGGACCAGATGGCAAAAACATACCA
ATTACAATCTGAATGCTATATTTAAAACCCTTAAATTCTGAAGGCCTGAATATCAACAAA
CCTATTTATGTTTATGATCCTAAAAAGACATTAAATATTATTAAACCCCCAACTTTCAAA
ACATAGAGACCCAGCAAACTGGGCTAGTGGTATCTCAGTACACAGTCACACATGACTAGA
CTAGACTAGACTAGACTAGACTAGAGATCTGAGTTTGCAACCAAGTACAAGAAGGTCTTT
AGGAGCTCAGGCTAAGGGAGGCACTTTATTCAATGCATGCCCTGANAAAGAGGGAAAGTA
CCTCGTATCCTAAACTATGTGGCCATCATATATCTACCTCAAGACATCTAGACACCGTAT
CTCCTCTTAACTGCCAGTCAGAACAAATTACTTTATTTGCAGCTAAATATTGCTTCCCTC
AGTGGAGAATAATTAGCAGCGACGAGACCAACTCCTGTTTAACCACTGGAAGAAAAGAAA
AGGGTAGTTTCTCCTTGGAATCCAAAGATTCTGCCTCGTCTGCGGTATAATT
Restriction Sites NotI-NotI |
ACCN NM_001310
Insert Size 2950 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001310.2, NP_001301.1
RefSeq Size 3748 bp
RefSeq ORF 363 bp
Locus ID 1389
UniProt ID O60519
Cytogenetics 12p13.1
Protein Families Transcription Factors
Summary cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. provided by RefSeq, Jul 2008
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Documents
Resources
"NM_001310" in other vectors (6)
SKU Description Size Price
RC210722 CREBL2 (Myc-DDK-tagged)-Human cAMP responsive element binding protein-like 2 (CREBL2) 10 ug
$150.00
RC210722L1 Lenti ORF clone of Human cAMP responsive element binding protein-like 2 (CREBL2), Myc-DDK-tagged 10 ug
$450.00
RC210722L2 Lenti ORF clone of Human cAMP responsive element binding protein-like 2 (CREBL2), mGFP tagged 10 ug
$450.00
RC210722L3 Lenti ORF clone of Human cAMP responsive element binding protein-like 2 (CREBL2), Myc-DDK-tagged 10 ug
$450.00
RC210722L4 Lenti ORF clone of Human cAMP responsive element binding protein-like 2 (CREBL2), mGFP tagged 10 ug
$450.00
RG210722 CREBL2 (tGFP-tagged) - Human cAMP responsive element binding protein-like 2 (CREBL2) 10 ug
$350.00

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