INPP5F (OCRL) (NM_001587) Human Untagged Clone
$819.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | INPP5F |
| Synonyms | Dent-2; DENT2; INPP5F; LOCR; NPHL2; OCRL-1; OCRL1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_001587 |
| Insert Size | 5120 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001587.3, NP_001578.2 |
| RefSeq Size | 5141 bp |
| RefSeq ORF | 2682 bp |
| Locus ID | 4952 |
| UniProt ID | Q01968 |
| Cytogenetics | Xq26.1 |
| Domains | Exo_endo_phos, IPPc, RhoGAP |
| Protein Families | Druggable Genome |
| Protein Pathways | Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system |
| Summary | This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. provided by RefSeq, Jan 2016 Transcript Variant: This variant (b) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform b) that has a shorter C-terminus, compared to isoform 1. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001587" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC210491 | OCRL (Myc-DDK-tagged)-Human oculocerebrorenal syndrome of Lowe (OCRL), transcript variant b | 10 ug |
$818.00
|
|
| RC210491L3 | Lenti-ORF clone of OCRL (Myc-DDK-tagged)-Human oculocerebrorenal syndrome of Lowe (OCRL), transcript variant b | 10 ug |
$1,118.00
|
|
| RC210491L4 | Lenti-ORF clone of OCRL (mGFP-tagged)-Human oculocerebrorenal syndrome of Lowe (OCRL), transcript variant b | 10 ug |
$1,118.00
|
|
| RG210491 | OCRL (tGFP-tagged) - Human oculocerebrorenal syndrome of Lowe (OCRL), transcript variant b | 10 ug |
$789.00
$1,018.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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