PABP (PABPC1) (NM_002568) Human Untagged Clone
$593.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | PABP |
| Synonyms | PAB1; PABP; PABP1; PABPC2; PABPL1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_002568 |
| Insert Size | 2570 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_002568.3, NP_002559.2 |
| RefSeq Size | 2869 bp |
| RefSeq ORF | 1911 bp |
| Locus ID | 26986 |
| UniProt ID | P11940 |
| Cytogenetics | 8q22.3 |
| Domains | PABP, RRM, RRM_1 |
| Summary | This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.provided by RefSeq, Aug 2010 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_002568" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC207354 | PABPC1 (Myc-DDK-tagged)-Human poly(A) binding protein, cytoplasmic 1 (PABPC1) | 10 ug |
$592.00
|
|
| RC207354L1 | Lenti ORF clone of Human poly(A) binding protein, cytoplasmic 1 (PABPC1), Myc-DDK-tagged | 10 ug |
$892.00
|
|
| RC207354L2 | Lenti ORF clone of Human poly(A) binding protein, cytoplasmic 1 (PABPC1), mGFP tagged | 10 ug |
$892.00
|
|
| RC207354L3 | Lenti ORF clone of Human poly(A) binding protein, cytoplasmic 1 (PABPC1), Myc-DDK-tagged | 10 ug |
$892.00
|
|
| RC207354L4 | Lenti ORF clone of Human poly(A) binding protein, cytoplasmic 1 (PABPC1), mGFP tagged | 10 ug |
$892.00
|
|
| RG207354 | PABPC1 (tGFP-tagged) - Human poly(A) binding protein, cytoplasmic 1 (PABPC1) | 10 ug |
$489.00
$792.00
|
|
Citations
Cell adhesion-induced transient interaction of ADAM15 with poly(A) binding protein at the cell membrane colocalizes with mRNA translation
Böhm, Fehrl, Janczi et al
PLoS ONE (2018) 13 (9), e0203847 DOI: 10.1371/journal.pone.0203847
Böhm, Fehrl, Janczi et al
PLoS ONE (2018) 13 (9), e0203847 DOI: 10.1371/journal.pone.0203847
AI Summary: OriGene’s PABP vector was used as a template to amplify various PABP domains by PCR, enabling the study of ADAM15’s interaction with PABP in the context of cell adhesion and mRNA translation.
Snippet: plasmic domain of ADAM15 (amino acids 717–814) was cloned as described previously (30). A myc-tag was attached to the C-terminus. The various PABP domains were amplified by PCR using a PABP vector (OriGene) as template and cloned using the primer combinations listed under mammalian-two hybrid. The correctness of the amplified nucleotide sequence was confirmed by sequencing. Protein expression wa
Divergent GW182 functional domains in the regulation of translational silencing
Yao, Li, Jung et al
Nucleic Acids Res. (2011) 39 (7), 2534-47 DOI: 10.1093/nar/gkq1099
Yao, Li, Jung et al
Nucleic Acids Res. (2011) 39 (7), 2534-47 DOI: 10.1093/nar/gkq1099
Cited by 32
AI Summary: OriGene contributed to this study by providing the PABPC1 expression vector, which was used to investigate the interactions and functional roles of GW182 domains in translational silencing.
Snippet: Piscataway, NJ, USA). The cDNA of Δ12a mutant (Δ12am, all GW or WG changed to AA) was also synthesized by GenScript. The PABPC1 expression vector was purchased from OriGene (Rockville, MD, USA). All of the variants
Showing 1-2 of 2 papers.
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