RING1 (NM_002931) Human Untagged Clone

SKU SC118280

RING1 (untagged)-Human ring finger protein 1 (RING1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: RING1
• Synonyms: RING1A; RNF1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_002931, the custom clone sequence may differ by one or more nucleotides; ; ; ATGACGACGCCGGCGAATGCCCAGAATGCCAGCAAAACGTGGGAACTGAGTCTGTATGAGCTGCACCGGA; CCCCGCAGGAAGCCATAATGGATGGCACAGAGATTGCTGTTTCCCCTCGGTCACTGCATTCAGAACTCAT; GTGCCCTATCTGCCTGGACATGCTGAAGAATACGATGACCACCAAGGAGTGCCTCCACAGATTCTGCTCT; GACTGCATTGTCACAGCCCTACGGAGCGGGAACAAGGAGTGTCCTACCTGCCGAAAGAAGCTGGTGTCCA; AGCGATCCCTACGGCCAGACCCCAACTTTGATGCCCTGATCTCTAAGATCTATCCTAGCCGGGAGGAATA; CGAGGCCCATCAAGACCGAGTGCTTATCCGCCTGAGCCGCCTGCACAACCAGCAGGCATTGAGCTCCAGC; ATTGAGGAGGGGCTACGCATGCAGGCCATGCACAGGGCCCAGCGTGTGAGGCGGCCGATACCAGGGTCAG; ATCAGACCACAACGATGAGTGGGGGGGAAGGAGAGCCCGGGGAGGGAGAAGGGGATGGAGAAGATGTGAG; CTCAGACTCCGCCCCTGACTCTGCCCCAGGCCCTGCTCCCAAGCGACCCCGTGGAGGGGGCGCAGGGGGG; AGCAGTGTAGGGACAGGGGGAGGCGGCACTGGTGGGGTGGGTGGGGGTGCCGGTTCGGAAGACTCTGGTG; ACCGGGGAGGGACTCTGGGAGGGGGAACGCTGGGCCCCCCAAGCCCTCCTGGGGCCCCCAGCCCCCCAGA; GCCAGGTGGAGAAATTGAGCTCGTGTTCCGGCCCCACCCCCTGCTCGTGGAGAAGGGAGAATACTGCCAG; ACGAGGTATGTGAAGACAACTGGGAATGCCACAGTGGACCACCTCTCCAAGTACTTGGCCCTGCGCATTG; CCCTCGAGCGGAGGCAACAGCAGGAAGCAGGGGAGCCAGGAGGGCCTGGAGGGGGCGCCTCTGACACCGG; AGGACCTGATGGGTGTGGCGGGGAGGGTGGGGGTGCCGGAGGAGGTGACGGTCCTGAGGAGCCTGCTTTG; CCCAGCCTGGAGGGCGTCAGTGAAAAGCAGTACACCATCTACATCGCACCTGGAGGCGGGGCGTTCACGA; CGTTGAATGGCTCGCTGACCCTGGAGCTGGTGAATGAGAAATTCTGGAAGGTGTCCCGGCCACTGGAGCT; GTGCTATGCTCCCACCAAGGATCCAAAGTGA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002931 unedited; GCACGAGGCGGCGGTGGCGGGAGCTGCTGTCTGAGCAGCGGTTGCGGACCGAGCGAACTT; GGCCCAGGAGCCCGGGCCTAGGGAGAGGCGCGGCGGCGGCGGGAGCGCGAACGGCTGGAG; CTGGCCTTCTTCGCCTTCTCCTCGGCTGTGGAGCCCTGGTGGGGGGTCTGCGCCCGGTCA; CCATGACGACGCCGGCGAATGCCCAGAATGCCAGCAAAACGTGGGAACTGAGTCTGTATG; AGCTGCACCGGACCCCGCAGGAAGCCATAATGGATGGCACAGAGATTGCTGTTTCCCCTC; GGTCACTGCATTCAGAACTCATGTGCCCTATCTGCCTGGACATGCTGAAGAATACGATGA; CCACCAAGGAGTGCCTCCACAGATTCTGCTCTGACTGCATTGTCACAGCCCTACGGAGCG; GGAACAAGGAGTGTCCTACCTGCCGAAAGAAGCTGGTGTCCAAGCGATCCCTACGGCCAG; ACCCCAACTTTGATGCCCTGATCTCTAAGATCTATCCTAGCCGGGAGGAATACGAGGCCC; ATCAAGACCGAGTGCTTATCCGCCTGAGCCGCCTGCACAACCAGCAGGCATTGAGCTCCA; GCATTGAGGAGGGGCTACGCATGCAGGCCATGCACAGGGCCCAGCGTGTGAGGCGGCCGA; TACCAGGGTCAGA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002931 unedited; CATGGATGCTGCCCCAATTCANGTTTTTTTTCAAAAACCAAAAAAGCCGTTTGTTGTTGG; TAGGCGGGCGTGAATGGGAGGGTTCTTCACCTTCTCCAACACCTCGTATAGATGGGACGT; TGCAGGGCAATAGAAAAGGCAGCAGATGGGGGCGTGTTTTGCCCCACTCTGTACAATATA; GAAGAATCTCATATAGATACTTTGTATAAAAGCCACGTGTCCTCATTTGTGTCCTCTTAT; TGGCTGGCTGGGCTGGGGGTACTGGGGGACAAAGAAGCTGGGGTGATAGACCAGGACACA; GGGATACCCCATGGTCCCCTTCCTCTGGCTGTCCCCTGGTGGGGTCACTTTGGATCCTTG; GTGGGAGCATAGCACAGCTCCAGTGGCCGGGACACCTTCCAGAATTTCTCATTCACCAGC; TCCAGGGTCAGCGAGCCATTCAACGTCGTGAACGCCCCGCCTCCAGGTGCGATGTAGATG; GTGTACTGCTTTTCACTGACGCCCTCCAGGCTGGGCAAAGCAGGCTCCTCAGGACCGTCA; CCTCCTCCGGCACCCCCACCCTCCCCGCCACACCCATCAGGTCCTCCGGTGTCAGAGGCG; CCCCCTCCAGGCCCTCCTGGCTCCCCTGCTTCCTGCTGTTGCCTCCGCTCGAGGGCAATG; CGCAGGGCCAAGTACTTGGAGAGGTGGTCCACTGTGGCATTCCCAGTTGTCTTCACATAC; CTCGTCTGGCAGTATTCTCCCTTCTCCACGAGCAGGGGGTGGGGCCGGAACACGAGCTCA; ATTTCTCCACCTGGCTCTGGNGGGCTGGNGGCCCCCAGAGGGCTTGGGGGGCCCAGCGTC; CNCCTCCNAGAGTCCCTCCNCGGGTCACAGAGTCTTNCGAACCGGNNACCNNCACCACCC; NACCAGTGGCCGNNCTCCCCTGTCCCTACACTGGNTCCCCCCTGCGCCCCCTCCACGGGG; TCGCTT;
• Restriction Sites: NotI-NotI
• ACCN: NM_002931
• Insert Size: 2000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002931.3, NP_002922.2
• RefSeq Size: 1744 bp
• RefSeq ORF: 1221 bp
• Locus ID: 6015
• UniProt ID: Q06587
• Cytogenetics: 6p21.32
• Domains: RING
• Protein Families: Druggable Genome, Transcription Factors
• Summary: This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. [provided by RefSeq, Jul 2008]