STAT5A (NM_003152) Human Untagged Clone
$1,845.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | STAT5A |
| Synonyms | MGF; STAT5 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | |
| Restriction Sites | NotI-NotI | |
| ACCN | NM_003152 |
| Insert Size | 4314 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_003152.2, NP_003143.2 |
| RefSeq Size | 4314 bp |
| RefSeq ORF | 4314 bp |
| Locus ID | 6776 |
| UniProt ID | P42229, A0A384N5W4, A8K6I5, Q59GY7 |
| Cytogenetics | 17q21.2 |
| Domains | SH2, STAT |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors |
| Protein Pathways | Acute myeloid leukemia, Chronic myeloid leukemia, ErbB signaling pathway, Jak-STAT signaling pathway, Pathways in cancer |
| Summary | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Dec 2013 Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1). |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_003152" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC205753 | STAT5A (Myc-DDK-tagged)-Human signal transducer and activator of transcription 5A (STAT5A) | 10 ug |
$589.00
$1,090.00
|
|
| RC205753L1 | Lenti-ORF clone of STAT5A (Myc-DDK-tagged)-Human signal transducer and activator of transcription 5A (STAT5A) | 10 ug |
$1,390.00
|
|
| RC205753L2 | Lenti-ORF clone of STAT5A (mGFP-tagged)-Human signal transducer and activator of transcription 5A (STAT5A) | 10 ug |
$1,390.00
|
|
| RC205753L3 | Lenti-ORF clone of STAT5A (Myc-DDK-tagged)-Human signal transducer and activator of transcription 5A (STAT5A) | 10 ug |
$1,390.00
|
|
| RC205753L4 | Lenti-ORF clone of STAT5A (mGFP-tagged)-Human signal transducer and activator of transcription 5A (STAT5A) | 10 ug |
$1,390.00
|
|
| RG205753 | STAT5A (tGFP-tagged) - Human signal transducer and activator of transcription 5A (STAT5A) | 10 ug |
$789.00
$1,290.00
|
|
Citations
STAT5A-mediated NOX5-L expression promotes the proliferation and metastasis of breast cancer cells
Dho, Kim, Lee et al
Exp. Cell Res. (2016)
Dho, Kim, Lee et al
Exp. Cell Res. (2016)
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
