JUND (NM_005354) Human Untagged Clone

SKU SC116768

JUND (untagged)-Human jun D proto-oncogene (JUND)

Product Data

• Type: Human Untagged Clone
• Target Symbol: JUND
• Synonyms: AP-1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005354, the custom clone sequence may differ by one or more nucleotides; ; ; ATGGAAACACCCTTCTACGGCGATGAGGCGCTGAGCGGCCTGGGCGGCGGCGCCAGTGGCAGCGGCGGCA; GCTTCGCGTCCCCGGGCCGCTTGTTCCCCGGGGCGCCCCCGACGGCCGCGGCCGGCAGCATGATGAAGAA; GGACGCGCTGACGCTGAGCCTGAGTGAGCAGGTGGCGGCAGCGCTCAAGCCTGCGGCCGCGCCGCCTCCT; ACCCCCCTGCGCGCCGACGGCGCCCCCAGCGCGGCACCCCCCGACGGCCTGCTCGCCTCTCCCGACCTGG; GGCTGCTGAAGCTGGCCTCCCCCGAGCTCGAGCGCCTCATCATCCAGTCCAACGGGCTGGTCACCACCAC; GCCGACGAGCTCACAGTTCCTCTACCCCAAGGTGGCGGCCAGCGAGGAGCAGGAGTTCGCCGAGGGCTTC; GTCAAGGCCCTGGAGGATTTACACAAGCAGAACCAGCTCGGCGCGGGCGCGGCCGCTGCCGCCGCCGCCG; CCGCCGCCGGGGGGCCCTCGGGCACGGCCACGGGCTCCGCGCCCCCCGGCGAGCTGGCCCCGGCGGCGGC; CGCGCCCGAAGCGCCTGTCTACGCGAACCTGAGCAGCTACGCGGGCGGCGCCGGGGGCGCGGGGGGCGCC; GCGACGGTCGCCTTCGCTGCCGAACCTGTGCCCTTCCCGCCGCCGCCACCCCCAGGCGCGTTGGGGCCGC; CGCGCCTGGCTGCGCTCAAGGACGAGCCACAGACGGTGCCCGACGTGCCGAGCTTCGGCGAGAGCCCGCC; GTTGTCGCCCATCGACATGGACACGCAGGAGCGCATCAAGGCGGAGCGCAAGCGGCTGCGCAACCGCATC; GCCGCCTCCAAGTGCCGCAAGCGCAAGCTGGAGCGCATCTCGCGCCTGGAAGAGAAAGTGAAGACCCTCA; AGAGTCAGAACACGGAGCTGGCGTCCACGGCGAGCCTGCTGCGCGAGCAGGTGGCGCAGCTCAAGCAGAA; AGTCCTCAGCCACGTCAACAGCGGCTGCCAGCTGCTGCCCCAGCACCAGGTGCCCGCGTACTGA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005354 unedited; TGTCGGGATAGGNATACGATTCATATAGGCGGCCGCCGAATTCGCACGAGGGATGGAAAC; ACCCTTCTACGGCGATGAGGCGCTGAGCGGCCTGGGCGGCGGCGCCAGTGGCAGCGGCGG; CAGCTTCGCGTCCCCGGGCCGCTTGTTCCCCGGGGCGCCCCCGACGGCCGCGGCCGGCAG; CATGATGAAGAAGGACGCGCTGACGCTGATCCTGAGTGAGCAGGTGGCGGCAGCGCTCAA; GCCTGCGGCCGCGCCGCCTCCTACCCCCCTGCGCGCCGACGGCGCCCCCAGCGCGGCACC; CCCCGACGGCCTGCTCGCCTCTCCCGACCTGGGGCTGCTGAAGCTGGCCTCCCCCGAGCT; CGAGCGCCTCATCATCCAGTCCAACGGGCTGGTCACCACCACGCCGACGAGCTCACAGTT; CCTCTACCCCAAGGTGGCGGCCAGCGAGGAGCAGGAGTTCGCCGAGGGCTTCGTCAAGGC; CCTGGAGGATTTACACAAGCAGAACCAGCTCGGCGCGGGCGCGGCCGCTGCCGCCGCCGT; CGCCGCCGTCGGGGGGCCCTCGGGCACGGCCACCGGCTCCGCGCCTCCGGCGAGTTGGCC; CCGGCGGGGCCGCGCCCGAAGCGCCTGTCTACCCGAACCTGATCGCTTCCCCGGCCGCGC; CGGGGGCGCCGGGGGCGCCCCGACCGCCGCCTTTCCTGCCGAACTTGTGTCCTTTCCGTC; GCCGCCACCCCCCAGCCCTGTTGGGCCCGCCGCGCCTGGCTTGGCTTAAAGACCACCCCC; ATACGGTGCCCCGACGTTCCCCACTTTCGCGAGAACCCGCCGTTGTTCGCCCTCGACTGG; GCCACCCAGGATCCCTCCAGGCGGTCACCAAACGGCTGTCCACCGCAATGCGTCTCTAAT; GCCCAAGCGCAATTG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005354 unedited; GGACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGCGTAACGAGACT; TTACTGAAAACAGAAAACCGGGCGAACCAAGGATTACAAACAGGAATGTGGACTCGTAGC; AAAACAAAACAAAACAGAACAAAAAAGGGAGGGGGGACCGGTCGAAAGAACCGAAGGGGG; GAGCGAGATCGAGGAAAGGGGCGGAGAATTTTTTTTTCTTCTTCCCATTTCTTTAAAAAA; CCAACACAAGAAAACACACACACACACAACCAACGTTTGTTCCCGAGTAGAAACATAAAT; AGGGCAGAATCGAACACTCTGTTCTTCTCTCTTCCAAAGGAAAAAAAAAAAAAGTAAAAG; TAAAGGAAAGGCAGGGTTTGAGGCTGCGCCCCCTCGGAGCCTCCTTCCGCGGCGCGGTGT; ACAAAGGGGCAGCCGAGACGCGCGGGTTTGTGCAACACGGGGCGGCCGCGCGGGGGAAAG; AGGCATCGCGAGGGCGGGGGGGTCATGCGCTCCTCCCACCGGAAGCAGGGGGAACATCTT; GATAAGAACGGGGCGCCCCTTCCCAGAGCTGGATCACTTGGGGGGGAATTAACGGGGACC; CACACTCCACTACACAACTGGACACACTTAAATAGGGACCTTTTTCCTTCTTTTCTCCCC; CCCTTCCCCCCCCCCCTCACTAAATATGCCTACCGCTCACCTGTCCTCCTGCTCATATTG; TATATTAATTAAACAATATCTCTGATCCCCCCCCCCCCGCCTCACTCCTCCCTCATCTTC; TCCCACCAGCCCCCCCCCCCCCAGCGATTTCCTTTCTCCCCCCCCTCCCCTCCTTCTCTC; AAATTTTACGCCTCCGCTCTTTCTACTCTCTTCTCCGCGCCACATCATCCTTGGTTACTC; CATACTTG;
• Restriction Sites: NotI-NotI
• ACCN: NM_005354
• Insert Size: 1280 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005354.2, NP_005345.2
• RefSeq Size: 1891 bp
• RefSeq ORF: 1044 bp
• Locus ID: 3727
• UniProt ID: P17535
• Cytogenetics: 19p13.11
• Domains: BRLZ, Jun
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: MAPK signaling pathway
• Summary: The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013]; Transcript Variant: This variant (1) encodes two isoforms resulting from the use of alternative in-frame translation initiation codons. The longer isoform (JunD-FL) is derived from an upstream AUG (S1 ORF, PMID:12105216), while the shorter isoform (deltaJunD) is derived from a downstream AUG (S3 ORF, PMID:12105216). This RefSeq represents the longer isoform (JunD-FL).